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Literature summary extracted from

  • Jaken, S.; Mason, M.
    Purification and comparison of several catalytic parameters of the gamma-glutamyltranspeptidase of rat mammary adenocarcinoma (13762) and of normal rat mammary gland (1979), Biochim. Biophys. Acta, 568, 331-338.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.2.2 glutathione L-Glu-4-nitroanilide as substrate Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.2.2 0.9
-
 L-Glu-4-nitroanilide carcinoma enzyme Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.2.2 membrane
-
 Rattus norvegicus 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.2.2 additional information
-
 amino acid composition Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.2 Rattus norvegicus
-
 multiparous rats
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.2.2 from carcinoma and partially from normal mammary gland Rattus norvegicus
2.3.2.2 Triton X-100 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.2.2 mammary carcinoma cell transplantable, MT 13762 Rattus norvegicus
-
2.3.2.2 mammary gland
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.2.2 1.3
-
 partially purified from mammary gland Rattus norvegicus
2.3.2.2 1320
-
 purified enzyme from mammary carcinoma Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.2 (5-L-glutamyl)-peptide + acceptor + H+
-
 Rattus norvegicus peptide + 5-L-glutamyl amino acid
-
 ?
2.3.2.2 5-L-glutamyl-4-nitroanilide + citrulline
-
 Rattus norvegicus 4-nitroaniline + 5-L-glutamyl-citrulline
-
 ?
2.3.2.2 5-L-glutamyl-4-nitroanilide + glycylglycine best acceptor Rattus norvegicus 4-nitroaniline + 5-L-glutamylglycylglycine
-
 ?
2.3.2.2 5-L-glutamyl-4-nitroanilide + L-alanine
-
 Rattus norvegicus 4-nitroaniline + 5-L-glutamyl-L-alanine
-
 ?
2.3.2.2 5-L-glutamyl-4-nitroanilide + L-arginine
-
 Rattus norvegicus 4-nitroaniline + 5-L-glutamyl-L-arginine
-
 ?
2.3.2.2 5-L-glutamyl-4-nitroanilide + L-cystine
-
 Rattus norvegicus 4-nitroaniline + 5-L-glutamyl-L-cystine
-
 ?
2.3.2.2 5-L-glutamyl-4-nitroanilide + L-glutamate
-
 Rattus norvegicus 4-nitroaniline + 5-L-glutamyl-L-glutamate
-
 ?
2.3.2.2 5-L-glutamyl-4-nitroanilide + L-glutamine
-
 Rattus norvegicus 4-nitroaniline + 5-L-glutamyl-L-glutamine
-
 ?
2.3.2.2 5-L-glutamyl-4-nitroanilide + L-lysine
-
 Rattus norvegicus 4-nitroaniline + 5-L-glutamyl-L-lysine
-
 ?
2.3.2.2 5-L-glutamyl-4-nitroanilide + L-methionine
-
 Rattus norvegicus 4-nitroaniline + 5-L-glutamyl-L-methionine
-
 ?
2.3.2.2 L-Glu-4-nitroanilide + glutathione
-
 Rattus norvegicus 4-nitroaniline + 5-L-glutamyl-glutathione
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.2.2 1.17
-
 glutathione carcinoma enzyme Rattus norvegicus