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Literature summary extracted from

  • Seitz, J.; Keppler, C.; Huntemann, S.; Rausch, U.; Aumuller, G.
    Purification and molecular characterization of a secretory transglutaminase from coagulating gland of the rat (1991), Biochim. Biophys. Acta, 1078, 139-146.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.2.13 EDTA complete inactivation above 10 mM Rattus norvegicus
2.3.2.13 additional information transglutaminase of coagulating gland, not inhibited by GTP Rattus norvegicus
2.3.2.13 NH4+ complete inhibition of coagulating gland transglutaminase with more than 1 mM NH4Cl or 20 mM (NH4)2SO4 Rattus norvegicus
2.3.2.13 Sodium citrate above 10 mM, complete inactivation Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.2.13 Ca2+ requirement Rattus norvegicus
2.3.2.13 Ca2+ 0.5 mM, maximum activity of transglutaminase from coagulating gland Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.2.13 65000
-
 transglutaminase C, gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.13 Rattus norvegicus
-
 mature male Wistar
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.3.2.13 glycoprotein coagulating gland transglutaminase, glycosylated with mannosyl-residues, no terminal position, substituted with saturated acyl residues and phosphoinositol Rattus norvegicus

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.2.13
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.2.13 coagulating gland secretion, not immunologically related to tissue-type enzyme or blood factor XIIIa Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.13 putrescine + N,N'-dimethylcasein
-
 Rattus norvegicus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.2.13 additional information
-
 pI: 8.5-8.7, purified enzyme Rattus norvegicus
2.3.2.13 additional information
-
 pI: 7.6, crude enzyme Rattus norvegicus