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Literature summary extracted from

  • Kawashima, S.
    Inhibition of rat liver transglutaminase by nucleotides (1991), Experientia, 47, 709-712.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.2.13 ADP complete inhibition of rat liver and human brain transglutaminase, reversible, non-competitive to putrescine Homo sapiens
2.3.2.13 ADP complete inhibition of rat liver and human brain transglutaminase, reversible, non-competitive to putrescine Rattus norvegicus
2.3.2.13 AMP weak inhibition of liver transglutaminase Rattus norvegicus
2.3.2.13 ATP 3 mM, complete inhibition of rat liver and human brain tissue-type transglutaminase, reversible; 3 mM, complete inhibition of rat liver and human brain transglutaminase, reversible, non-competitive to putrescine Homo sapiens
2.3.2.13 ATP 3 mM, complete inhibition of rat liver and human brain tissue-type transglutaminase, reversible; 3 mM, complete inhibition of rat liver and human brain transglutaminase, reversible, non-competitive to putrescine Rattus norvegicus
2.3.2.13 CTP 3 mM, complete inhibition of rat liver and human brain transglutaminase, reversible, non-competitive to putrescine Homo sapiens
2.3.2.13 CTP 3 mM, complete inhibition of rat liver and human brain transglutaminase, reversible, non-competitive to putrescine Rattus norvegicus
2.3.2.13 GTP 50% as effective as ATP Homo sapiens
2.3.2.13 GTP 50% as effective as ATP Rattus norvegicus
2.3.2.13 additional information
-
 Homo sapiens
2.3.2.13 additional information not inhibited by adenosine or adenine Rattus norvegicus
2.3.2.13 UTP 50% as effective as ATP Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.2.13 Ca2+ requirement Homo sapiens
2.3.2.13 Ca2+ requirement Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.13 Homo sapiens
-
-
-
2.3.2.13 Rattus norvegicus
-
 tissue-type transglutaminase, abbrevation TGC
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.2.13 partial Homo sapiens
2.3.2.13 tissue-type transglutaminase Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.2.13 brain
-
 Homo sapiens
-
2.3.2.13 brain
-
 Rattus norvegicus
-
2.3.2.13 liver
-
 Homo sapiens
-
2.3.2.13 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.13 putrescine + N,N'-dimethylcasein
-
 Homo sapiens ?
-
 ?
2.3.2.13 putrescine + N,N'-dimethylcasein
-
 Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.2.13 transglutaminase C
-
 Rattus norvegicus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.2.13 37
-
 assay at Homo sapiens
2.3.2.13 37
-
 assay at Rattus norvegicus