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Literature summary extracted from

  • Cerna, J.; Rychlik, I.
    Phenylboric acids - A new group of peptidyl transferase inhibitors (1980), FEBS Lett., 119, 342-348.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.2.12 m-nitrophenylboric acid more potent inhibitor than phenylboric acid Escherichia coli
2.3.2.12 phenylboric acid
-
 Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.2.12 ribosome
-
 Escherichia coli 5840
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.12 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.12 2'(3')-O-(N-formylmethionyl)-adenosine-5'-phosphate + CACCA-Phe
-
 Escherichia coli ?
-
 ?
2.3.2.12 AcPhe-tRNA + puromycin
-
 Escherichia coli tRNA + AcPhe-puromycin
-
 ?
2.3.2.12 CACCA-AcLeu + puromycin fragment reaction Escherichia coli CACCA + AcLeu-puromycin
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.2.12 0.46
-
 m-nitrophenylboric acid
-
 Escherichia coli
2.3.2.12 0.52
-
 phenylboric acid
-
 Escherichia coli