EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.2.12 | cytidylyl-3'-5'-/2'(3')-O-L-phenylalanyl/L-adenosine | 50% inhibition of peptidyltransferase, inhibition can be reversed by increasing concentration of puromycin | Escherichia coli |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.3.2.12 | ribosome | 70S ribosomes | Escherichia coli | 5840 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.3.2.12 | Mg2+ | - |
Escherichia coli |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.2.12 | peptidyl-tRNA1 + alpha-aminoacyl-tRNA2 | Escherichia coli | - |
tRNA1 + peptidyl-amino-tRNA2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.2.12 | Escherichia coli | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.2.12 | N-AcPhe-tRNA + puromycin | - |
Escherichia coli | tRNA + N-AcPhe-puromycin | - |
? | |
2.3.2.12 | peptidyl-tRNA1 + alpha-aminoacyl-tRNA2 | - |
Escherichia coli | tRNA1 + peptidyl-amino-tRNA2 | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.3.2.12 | 37 | - |
enzyme assay | Escherichia coli |