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Literature summary extracted from

  • McIlhinney, R.A.; Young, K.; Egerton, M.; Camble, R.; White, A.; Soloviev, M.
    Characterization of human and rat brain myristoyl-CoA:protein N-myristoyltransferase: evidence for an alternative splice variant of the enzyme (1998), Biochem. J., 333, 491-495.
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.97 gene cloned from cell culture and lymphocytes, in vitro translation of 2 different splice variants, DNA and amino acid sequence determination Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.97 additional information
-
-
 Rattus norvegicus
2.3.1.97 additional information
-
 amino acid sequence, alignment Homo sapiens
2.3.1.97 48000
-
 1 * 48000, splice variant 2, SDS-PAGE Rattus norvegicus
2.3.1.97 48000
-
 1 * 48000, splice variant 2 from in vitro translation, also recombinant enzyme from Escherichia coli, SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.97 Homo sapiens
-
 2 different splice variants
-
2.3.1.97 Rattus norvegicus
-
 2 different splice variants
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.97 recombinant from Escherichia coli Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.97 brain
-
 Rattus norvegicus
-
2.3.1.97 HEK-293 cell
-
 Homo sapiens
-
2.3.1.97 HeLa cell
-
 Homo sapiens
-
2.3.1.97 lymphocyte
-
 Homo sapiens
-
2.3.1.97 additional information 2 different splicing variants occur in rat tissues, the 62 kDa variant is abundant in most tissues, the 42 kDa variant occurs in brain and stomach Rattus norvegicus
-
2.3.1.97 stomach
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.97 myristoyl-CoA + glycylpeptide
-
 Homo sapiens N-myristoylglycylpeptide + CoA
-
 ?
2.3.1.97 myristoyl-CoA + glycylpeptide
-
 Rattus norvegicus N-myristoylglycylpeptide + CoA
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.97 monomer 1 * 62000-63000, splice variant 1, SDS-PAGE Homo sapiens
2.3.1.97 monomer 1 * 62000-63000, splice variant 1, SDS-PAGE Rattus norvegicus
2.3.1.97 monomer 1 * 48000, splice variant 2, SDS-PAGE Rattus norvegicus
2.3.1.97 monomer 1 * 48000, splice variant 2 from in vitro translation, also recombinant enzyme from Escherichia coli, SDS-PAGE Homo sapiens
2.3.1.97 More 2 different splice variants with 48000 Da and 63000 Da Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.3.1.97 NMT
-
 Homo sapiens
2.3.1.97 NMT
-
 Rattus norvegicus