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Literature summary extracted from

  • Duronio, R.J.; Rudnick, D.A.; Adams, S.P.; Towler, D.A.; Gordon, J.I.
    Analyzing the substrate specificity of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase by co-expressing it with mammalian G protein alpha subunits in Escherichia coli (1991), J. Biol. Chem., 266, 10498-10504.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.97 expression in Escherichia coli JM101, coexpression of each of the 4 homologous rat alpha subunits of the signal-transducing, heterotrimeric G proteins to determine in vivo interaction of the 2 enzymes, structural analysis Saccharomyces cerevisiae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.97 additional information
-
 additional information overview: Km values for glycylpeptides with varying amino acids sequence, influence of amino acid residue type and substitutions on affinity Saccharomyces cerevisiae
2.3.1.97 0.0001
-
 Gly-Asn-Ala-Ala-Ser-Ala-Arg-Arg
-
 Saccharomyces cerevisiae
2.3.1.97 0.06
-
 Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg
-
 Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.97 myristoyl-CoA + protein Saccharomyces cerevisiae proteins involved in metabolic regulation, e.g. catalytic subunit of protein kinase A and G protein alpha subunit ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.97 Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.97 11-oxatetradecanoyl-CoA + G0alpha-hexapeptide
-
 Saccharomyces cerevisiae N-11-oxatetradecanoyl-G0alpha-hexapeptide + CoA
-
 ?
2.3.1.97 13-oxatetradecanoyl-CoA + G0alpha-hexapeptide
-
 Saccharomyces cerevisiae N-13-oxatetradecanoyl-G0alpha-hexapeptide + CoA
-
 ?
2.3.1.97 6-oxatetradecanoyl-CoA + G0alpha-hexapeptide
-
 Saccharomyces cerevisiae N-6-oxatetradecanoyl-G0alpha-hexapeptide + CoA
-
 ?
2.3.1.97 myristoyl-CoA + Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg
-
 Saccharomyces cerevisiae N-myristoyl-Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg + CoA
-
 ?
2.3.1.97 myristoyl-CoA + Gly-Asn-Ala-Ala-Ser-Ala-Arg-Arg
-
 Saccharomyces cerevisiae N-myristoyl-Gly-Asn-Ala-Ala-Ser-Ala-Arg-Arg + CoA
-
 ?
2.3.1.97 myristoyl-CoA + glycylpeptide substrate specificity Saccharomyces cerevisiae N-myristoylglycylpeptide + CoA
-
 ?
2.3.1.97 myristoyl-CoA + glycylpeptide overview peptides and proteins Saccharomyces cerevisiae N-myristoylglycylpeptide + CoA
-
 ?
2.3.1.97 myristoyl-CoA + protein proteins involved in metabolic regulation, e.g. catalytic subunit of protein kinase A and G protein alpha subunit Saccharomyces cerevisiae ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.97 NMT
-
 Saccharomyces cerevisiae