Literature summary extracted from

De Angelis, J.; Gastel, J.; Klein, D.C.; Cole, P.A.
Kinetic analysis of the catalytic mechanism of serotonin N-acetyltransferase (EC 2.3.1.87) (1998), J. Biol. Chem., 273, 3045-3050.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.3.1.87	desulfo-CoA	dead end inhibitor analog, competitive versus CoA	Ovis aries
2.3.1.87	tryptophol	dead end inhibitor analog, competitive versus tryptamine	Ovis aries

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.3.1.87	Ovis aries	-	glutathione S-transferase fusion protein, fused and cleaved form	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
2.3.1.87	acetyl-CoA + a 2-arylethylamine = CoA + an N-acetyl-2-arylethylamine	ordered bi-bi sequential mechanism	Ovis aries	a

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.3.1.87	acetyl-CoA + tryptophol	structural analogue to tryptamine	Ovis aries	CoA + N-acetyltryptophol	-	?

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Release 2023.1 (January 2023)