Literature summary extracted from
Katiyar, S.S.; Pan, D.; Porter, J.W.
Inactivation of 3-oxoacyl synthetase activity of pigeon liver fatty acid synthetase by S-(4-bromo-2,3-dioxobutyl)-coenzyme A (1983), Eur. J. Biochem., 130, 177-184.
Inhibitors
EC Number |
Inhibitors |
Comment |
Organism |
Structure |
---|
2.3.1.85 |
crotonyl-CoA |
dehydrase activity |
Columba sp. |
|
2.3.1.85 |
iodoacetamide |
kinetics, 50% inactivation after 5 min at 1 mM and after 0.5 min at 20 mM |
Columba sp. |
|
2.3.1.85 |
S-(4-bromo-2,3-dioxobutyl)-CoA |
irreversible, 50% inhibition after 10 s at 0.02 mM, 6.5 s at 0.06 mM and 4.5 s at 0.09 mM, specific for acetyl transacetylase and beta-ketoacyl synthase activity, 4 mol inhibitor per mol enzyme complex, acetyl-CoA, malonyl-CoA, cysteine and pantetheine protect |
Columba sp. |
|
Molecular Weight [Da]
EC Number |
Molecular Weight [Da] |
Molecular Weight Maximum [Da] |
Comment |
Organism |
---|
2.3.1.85 |
240000 |
- |
2 * 240000, SDS-PAGE |
Columba sp. |
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
2.3.1.85 |
Columba sp. |
- |
pigeon |
- |
Source Tissue
EC Number |
Source Tissue |
Comment |
Organism |
Textmining |
---|
2.3.1.85 |
liver |
- |
Columba sp. |
- |
Subunits
EC Number |
Subunits |
Comment |
Organism |
---|
2.3.1.85 |
dimer |
2 * 240000, SDS-PAGE |
Columba sp. |
Cofactor
EC Number |
Cofactor |
Comment |
Organism |
Structure |
---|
2.3.1.85 |
4'-phosphopantetheine |
location of active site |
Columba sp. |
|