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Literature summary extracted from

  • Katiyar, S.S.; Pan, D.; Porter, J.W.
    Inactivation of 3-oxoacyl synthetase activity of pigeon liver fatty acid synthetase by S-(4-bromo-2,3-dioxobutyl)-coenzyme A (1983), Eur. J. Biochem., 130, 177-184.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.85 crotonyl-CoA dehydrase activity Columba sp.
2.3.1.85 iodoacetamide kinetics, 50% inactivation after 5 min at 1 mM and after 0.5 min at 20 mM Columba sp.
2.3.1.85 S-(4-bromo-2,3-dioxobutyl)-CoA irreversible, 50% inhibition after 10 s at 0.02 mM, 6.5 s at 0.06 mM and 4.5 s at 0.09 mM, specific for acetyl transacetylase and beta-ketoacyl synthase activity, 4 mol inhibitor per mol enzyme complex, acetyl-CoA, malonyl-CoA, cysteine and pantetheine protect Columba sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.85 240000
-
 2 * 240000, SDS-PAGE Columba sp.

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.85 Columba sp.
-
 pigeon
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.85 liver
-
 Columba sp.
-

Subunits

EC Number Subunits Comment Organism
2.3.1.85 dimer 2 * 240000, SDS-PAGE Columba sp.

Cofactor

EC Number Cofactor Comment Organism Structure
2.3.1.85 4'-phosphopantetheine location of active site Columba sp.