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Literature summary extracted from

  • Riccio, M.L.; Docquier, J.D.; Dell'Amico, E.; Luzzaro, F.; Amicosante, G.; Rossolini, G.M.
    Novel 3-N-aminoglycoside acetyltransferase gene, aac(3)-Ic, from a Pseudomonas aeruginosa integron (2003), Antimicrob. Agents Chemother., 47, 1746-1748.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.81 expression in Escherichia coli DH5alpha Pseudomonas aeruginosa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.81 soluble
-
 Pseudomonas aeruginosa
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.81 Pseudomonas aeruginosa Q83V16 phenotype of VA-182/00
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.81 acetyl-CoA + amikacin wild-type and recombinant enzyme Pseudomonas aeruginosa CoA + N3'-acetylamikacin
-
 ?
2.3.1.81 acetyl-CoA + gentamicin wild-type and recombinant enzyme Pseudomonas aeruginosa CoA + N3'-acetylgentamicin
-
 ?
2.3.1.81 acetyl-CoA + isepamycin wild-type and recombinant enzyme Pseudomonas aeruginosa CoA + N3'-acetylisepamycin
-
 ?
2.3.1.81 acetyl-CoA + kanamycin wild-type and recombinant enzyme Pseudomonas aeruginosa CoA + N3'-acetylkanamycin
-
 ?
2.3.1.81 acetyl-CoA + neomycin wild-type and recombinant enzyme Pseudomonas aeruginosa CoA + N2'-acetylneomycin
-
 ?
2.3.1.81 acetyl-CoA + netilmicin wild-type and recombinant enzyme Pseudomonas aeruginosa CoA + N3'-acetylnetilmicin
-
 ?
2.3.1.81 acetyl-CoA + sisomicin wild-type and recombinant enzyme Pseudomonas aeruginosa CoA + N3'-acetylsisomicin
-
 ?
2.3.1.81 acetyl-CoA + spectinomycin wild-type and recombinant enzyme Pseudomonas aeruginosa CoA + N3'-acetylspectinomycin
-
 ?
2.3.1.81 acetyl-CoA + streptomycin wild-type and recombinant enzyme Pseudomonas aeruginosa CoA + ?
-
 ?
2.3.1.81 acetyl-CoA + tobramycin wild-type and recombinant enzyme Pseudomonas aeruginosa CoA + N3'-acetyltobramycin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.81 3-N-aminoglycoside acetyltransferase
-
-