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Literature summary extracted from

  • Saeed, A.; McMillin, J.B.; Wolkowicz, P.E.; Brouillette, W.J.
    Carnitine acyltransferase enzymic catalysis requires a positive charge on the carnitine cofactor (1993), Arch. Biochem. Biophys., 305, 307-312.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.7 3-acetoxy-5,5-dimethylhexanoic acid
-
 Columba sp.
2.3.1.7 3-hydroxy-5,5-dimethylhexanoic acid
-
 Columba sp.
2.3.1.7 R-(+)-3-hydroxy-5,5-dimethylhexanoic acid
-
 Columba sp.
2.3.1.7 S-(-)-3-hydroxy-5,5-dimethylhexanoic acid
-
 Columba sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.7 acetyl-CoA + carnitine Columba sp.
-
 O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine Columba sp.
-
 acylcarnitine + CoASH
-
 r
2.3.1.7 acylcarnitine + CoASH Columba sp.
-
 acyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH Columba sp.
-
 acetyl-CoA + carnitine
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.7 Columba sp.
-
 pigeon
-
2.3.1.7 Columba sp.
-
 commercial preparation, Sigma
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.7 breast muscle
-
 Columba sp.
-
2.3.1.7 muscle
-
 Columba sp.
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.7 acetyl-CoA + carnitine
-
 Columba sp. O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + L-(-)carnitine
-
 Columba sp. O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine
-
 Columba sp. acylcarnitine + CoASH
-
 r
2.3.1.7 acylcarnitine + CoASH
-
 Columba sp. acyl-CoA + carnitine
-
 r
2.3.1.7 additional information 3-hydroxy-5,5-dimethylhexanoic acid, 3-acetoxy-5,5-dimethylhexanoic acid, R-(+)-3-hydroxy-5,5-dimethylhexanoic acid and S-(-)-3-hydroxy-5,5-dimethylhexanoic acid are not substrates Columba sp. ?
-
 ?
2.3.1.7 additional information D-carnitine is no substrate Columba sp. ?
-
 ?
2.3.1.7 O-acetylcarnitine + CoASH
-
 Columba sp. acetyl-CoA + L-(-)carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Columba sp. acetyl-CoA + carnitine
-
 r

Synonyms

EC Number Synonyms Comment Organism
2.3.1.7 CAT
-
 Columba sp.

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.1.7 4.1
-
 3-acetoxy-5,5-dimethylhexanoic acid reverse direction Columba sp.
2.3.1.7 7.5
-
 S-(-)-3-hydroxy-5,5-dimethylhexanoic acid
-
 Columba sp.
2.3.1.7 8.3
-
 3-hydroxy-5,5-dimethylhexanoic acid
-
 Columba sp.
2.3.1.7 20.3
-
 R-(+)-3-hydroxy-5,5-dimethylhexanoic acid
-
 Columba sp.