Literature summary extracted from

Zambrzycka, A.; Alberghina, M.; Strosznajder, J.B.
Effects of aging and amyloid-b peptides on choline acetyltransferase activity in rat brain (2002), Neurochem. Res., 27, 277-281.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.3.1.6	amyloid beta peptide	the aggregated form of A-beta 25-35 decreased significantly enzyme activity only in the aged striatum	Rattus norvegicus
2.3.1.6	arachidonic acid	-	Rattus norvegicus
2.3.1.6	H2O2	-	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.3.1.6	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.3.1.6	brain	cortex	Rattus norvegicus	-
2.3.1.6	brain	triatum	Rattus norvegicus	-
2.3.1.6	hippocampus	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.3.1.6	acetyl-CoA + choline	-	Rattus norvegicus	acetylcholine + CoA	-	?

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Release 2023.1 (January 2023)