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Literature summary extracted from

  • Wagner, A.F.V.; Schultz, S.; Bomke, J.; Pils, T.; Lehmann, W.D.; Knappe, J.
    YfiD of Escherichia coli and Y06I of bacteriophage T4 as autonomous glycyl radical cofactors reconstituting the catalytic center of oxygen-fragmented pyruvate formate-lyase (2001), Biochem. Biophys. Res. Commun., 285, 456-462.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.54 Y06I autonomous glycyl radical cofactor, reconstituting the catalytic center of oxygen-fragmented enzyme Tequatrovirus T4
2.3.1.54 YfiD
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.3.1.54 YfiD
-
 Haemophilus influenzae
2.3.1.54 YfiD
-
 Yersinia pestis
2.3.1.54 YfiD
-
 Vibrio cholerae serotype O1
2.3.1.54 YfiD
-
 Pasteurella multocida
2.3.1.54 YfiD
-
 Escherichia coli
2.3.1.54 YfiD autonomous glycyl radical cofactor, reconstituting the catalytic center of oxygen-fragmented enzyme Escherichia coli

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.3.1.54
-
 Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.54 pyruvate + CoA Salmonella enterica subsp. enterica serovar Typhimurium
-
 acetyl-CoA + formate
-
 r
2.3.1.54 pyruvate + CoA Haemophilus influenzae
-
 acetyl-CoA + formate
-
 r
2.3.1.54 pyruvate + CoA Escherichia coli
-
 acetyl-CoA + formate
-
 r
2.3.1.54 pyruvate + CoA Tequatrovirus T4
-
 acetyl-CoA + formate
-
 r
2.3.1.54 pyruvate + CoA Yersinia pestis
-
 acetyl-CoA + formate
-
 r
2.3.1.54 pyruvate + CoA Vibrio cholerae serotype O1
-
 acetyl-CoA + formate
-
 r
2.3.1.54 pyruvate + CoA Pasteurella multocida
-
 acetyl-CoA + formate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.54 Escherichia coli
-
-
-
2.3.1.54 Escherichia coli P09373 PFL, SwissProt accession number
-
2.3.1.54 Haemophilus influenzae
-
-
-
2.3.1.54 Pasteurella multocida
-
-
-
2.3.1.54 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
2.3.1.54 Tequatrovirus T4
-
-
-
2.3.1.54 Vibrio cholerae serotype O1
-
-
-
2.3.1.54 Yersinia pestis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.54 acetyl-CoA + formate
-
 Escherichia coli pyruvate + CoA
-
 r
2.3.1.54 pyruvate + CoA
-
 Salmonella enterica subsp. enterica serovar Typhimurium acetyl-CoA + formate
-
 r
2.3.1.54 pyruvate + CoA
-
 Haemophilus influenzae acetyl-CoA + formate
-
 r
2.3.1.54 pyruvate + CoA
-
 Escherichia coli acetyl-CoA + formate
-
 r
2.3.1.54 pyruvate + CoA
-
 Tequatrovirus T4 acetyl-CoA + formate
-
 r
2.3.1.54 pyruvate + CoA
-
 Yersinia pestis acetyl-CoA + formate
-
 r
2.3.1.54 pyruvate + CoA
-
 Vibrio cholerae serotype O1 acetyl-CoA + formate
-
 r
2.3.1.54 pyruvate + CoA
-
 Pasteurella multocida acetyl-CoA + formate
-
 r

Synonyms

EC Number Synonyms Comment Organism
2.3.1.54 PFL
-
 Escherichia coli