Literature summary extracted from

Zaher, H.; Lindblad, W.J.; Jiang, W.; Doll, M.A.; Hein, D.W.; Svensson, C.K.
Acetyl CoA: arylamine N-acetyltransferase activity in rat hepatocytes cultured on different extracellular matrixes (1997), Toxicol. in Vitro, 11, 271-283.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.3.1.5	methotrexate	inhibits reaction with 4-aminobenzoic acid, but with sulfamethazine, possibly due to two different enzymes	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.3.1.5	Rattus norvegicus	-	hepatocyte primary culture	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.3.1.5	liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.3.1.5	acetyl-CoA + 4-aminobenzoic acid	-	Rattus norvegicus	CoA + 4-acetylaminobenzoic acid	-	?
2.3.1.5	acetyl-CoA + sulfamethazine	-	Rattus norvegicus	CoA + N-4-acetylsulfamethazine	-	?

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Release 2023.1 (January 2023)