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Literature summary extracted from

  • Iwersen, M.; Vandamme-Feldhaus, V.; Schauer, R.
    Enzymic 4-O-acetylation of N-acetylneuraminic acid in guinea-pig liver (1998), Glycoconj. J., 15, 895-904.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.44 CoA
-
 Cavia porcellus
2.3.1.44 MnCl2
-
 Cavia porcellus
2.3.1.44 p-chloromercuribenzoate
-
 Cavia porcellus
2.3.1.44 saponin
-
 Cavia porcellus
2.3.1.44 Triton-X
-
 Cavia porcellus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.44 0.00061
-
 acetyl-CoA
-
 Cavia porcellus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.44 acetyl-CoA + N-acetylneuraminate Cavia porcellus
-
 CoA + N-acetyl-4-O-acetylneuraminate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.44 Cavia porcellus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.44 liver
-
 Cavia porcellus
-
2.3.1.44 serum
-
 Cavia porcellus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.44 acetyl-CoA + N-acetylneuraminate
-
 Cavia porcellus CoA + N-acetyl-4-O-acetylneuraminate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.44 30
-
-
 Cavia porcellus

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
2.3.1.44
-
 55
-
 Cavia porcellus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.44 6.7
-
 in 70 mM potassium phosphate buffer and the presence of 90 mM KCl Cavia porcellus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.3.1.44 5 8.5
-
 Cavia porcellus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.1.44 0.0042
-
 CoA
-
 Cavia porcellus