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Literature summary extracted from

  • Furukawa, Y.; Urano, T.; Itoh, H.; Takahashi, C.; Kimura, S.
    Isolation and properties of rat plasma lecithin-cholesterol acyltransferase (1989), J. Biochem., 105, 962-967.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.3.1.43 apo-A-1 prevents inactivation in phosphate buffer Rattus norvegicus
2.3.1.43 less stable than human enzyme to ionic strength Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.43 Rattus norvegicus
-
 rat
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.43 precipitation from plasma with dextran sulfate-Ca2+ followed by DEAE-Sephadex A-50 and ion-exchange chromatography, rat enzyme is not absorbed on hydroxyapatite, which is employed for the purification of the human enzyme Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.43 plasma
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.43 0.14
-
 in cholesterol-lecithin vesicles activated with rat apolipoprotein A1 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.43 phosphatidylcholine + sterol
-
 Rattus norvegicus 1-acylglycerophosphocholine + sterol ester
-
 r