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Literature summary extracted from

  • Kitabatake, K.; Piran, U.; Kamio, Y.; Doi, Y.; Nishida, T.
    Purification of human plasma lecithin:cholesterol acyltransferase and its specificity towards the acyl acceptor (1979), Biochim. Biophys. Acta, 573, 145-154.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.43 apolipoprotein A-I required for hydrolysis of ester linkage at carbon-2 position of phosphatidylcholine and for transesterification Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.43 65000
-
 x * 65000, SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.43 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.43
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.43 plasma
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.43 additional information
-
-
 Homo sapiens
2.3.1.43 3.47
-
 in cholesterol-lecithin vesicles activated with apolipoprotein A1 Homo sapiens

Storage Stability

EC Number Storage Stability Organism
2.3.1.43 4°C, low ionic strength buffer, under nitrogen, 4 weeks Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.43 additional information long-chain primary alcohols can act as acyl acceptors Homo sapiens ?
-
 ?
2.3.1.43 additional information enzyme hydrolyses ester linkage at carbon-2 position of phosphatidylcholine Homo sapiens ?
-
 ?
2.3.1.43 phosphatidylcholine + sterol wide specificity for acyl acceptor: sterols with a beta-configuration at carbon-3 and trans fused A /B rings Homo sapiens 1-acylglycerophosphocholine + sterol ester
-
 r
2.3.1.43 phosphatidylcholine + sterol water as acyl acceptor: phospholipase activity Homo sapiens 1-acylglycerophosphocholine + sterol ester
-
 r

Subunits

EC Number Subunits Comment Organism
2.3.1.43 ? x * 65000, SDS-PAGE Homo sapiens