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Literature summary extracted from

  • Schlossman, D.M.; Bell, R.M.
    Microsomal sn-glycerol 3-phosphate and dihydroxyacetone phosphate acyltransferase activities from liver and other tissues (1977), Arch. Biochem. Biophys., 182, 737-742.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.42 deoxycholate slight stimulation Rattus norvegicus
2.3.1.42 Triton X-100 slight stimulation Rattus norvegicus
2.3.1.42 Triton X-100 above 0.2 mg/ml Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.42 deoxycholate above 0.2 mg/ml Rattus norvegicus
2.3.1.42 glycerol 3-phosphate tissue distribution Rattus norvegicus
2.3.1.42 N-ethylmaleimide microsomal enzyme: strong Rattus norvegicus
2.3.1.42 Triton X-100 above 0.2 mg/ml Rattus norvegicus
2.3.1.42 Trypsin
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.42 additional information
-
 additional information values for enzymes from various tissues Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.42 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.42 Rattus norvegicus
-
 female Charles River CD-strain
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.42 brain
-
 Rattus norvegicus
-
2.3.1.42 intestine mucosa Rattus norvegicus
-
2.3.1.42 kidney
-
 Rattus norvegicus
-
2.3.1.42 liver
-
 Rattus norvegicus
-
2.3.1.42 lung
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.42 acyl-CoA + dihydroxyacetone phosphate no acyl-donors are C4-C10-acyl-CoAs Rattus norvegicus CoA + acyldihydroxyacetone phosphate i.e. acylglycerone phosphate ?
2.3.1.42 dodecanoyl-CoA + dihydroxyacetone phosphate
-
 Rattus norvegicus CoA + dodecanoyldihydroxyacetone phosphate
-
 ?
2.3.1.42 oleoyl-CoA + dihydroxyacetone phosphate
-
 Rattus norvegicus CoA + oleoyldihydroxyacetone phosphate
-
 ?
2.3.1.42 palmitoyl-CoA + dihydroxyacetone phosphate best substrate Rattus norvegicus CoA + monopalmitoyldihydroxyacetone phosphate
-
 ?
2.3.1.42 stearoyl-CoA + dihydroxyacetone phosphate
-
 Rattus norvegicus CoA + stearoyldihydroxyacetone phosphate
-
 ?
2.3.1.42 tetradecanoyl-CoA + dihydroxyacetone phosphate i.e. myristoyl-CoA Rattus norvegicus CoA + tetradecanoyldihydroxyacetone phosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.42 23
-
 assay at Rattus norvegicus

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.3.1.42 44
-
 t1/2: 10 min Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.42 7 7.4
-
 Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.3.1.42 6.5 8.5 about half-maximal activity at pH 6.5 and pH 8.5 Rattus norvegicus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.1.42 additional information
-
 additional information values for enzymes from various tissues Rattus norvegicus
2.3.1.42 0.12
-
 glycerol 3-phosphate
-
 Rattus norvegicus