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Literature summary extracted from

  • Rock, C.O.; Fitzgerald, V.; Snyder, F.
    Properties of dihydroxyacetone phosphate acyltransferase in the harderian gland (1977), J. Biol. Chem., 252, 6363-6366.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.42 cholate 20fold activation, 4 mM Oryctolagus cuniculus
2.3.1.42 deoxycholate 20fold stimulation and solubilization of membrane-bound microsomal activity Oryctolagus cuniculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.42 Ca2+ in crude enzyme extract Oryctolagus cuniculus
2.3.1.42 glycerol 3-phosphate not Oryctolagus cuniculus
2.3.1.42 Mg2+ in crude enzyme extract Oryctolagus cuniculus
2.3.1.42 Mn2+ in crude enzyme extract Oryctolagus cuniculus
2.3.1.42 N-ethylmaleimide not peroxisomal enzyme Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.42 0.7
-
 dihydroxyacetone phosphate
-
 Oryctolagus cuniculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.42 microsome active site exposed to lumenal surface Oryctolagus cuniculus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.1.42 additional information no activation by EDTA Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.42 palmitoyl-CoA + dihydroxyacetone phosphate Oryctolagus cuniculus reaction in phosphatidic acid biosynthesis CoA + monopalmitoyldihydroxyacetone phosphate
-
 ?
2.3.1.42 palmitoyl-CoA + dihydroxyacetone phosphate Oryctolagus cuniculus peroxisomal enzyme involved in ether lipid biosynthesis CoA + monopalmitoyldihydroxyacetone phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.42 Oryctolagus cuniculus
-
 adult male New Zealand White
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.42 harderian gland
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.42 acyl-CoA + dihydroxyacetone phosphate
-
 Oryctolagus cuniculus CoA + acyldihydroxyacetone phosphate
-
 ?
2.3.1.42 palmitoyl-CoA + dihydroxyacetone phosphate
-
 Oryctolagus cuniculus CoA + monopalmitoyldihydroxyacetone phosphate
-
 ?
2.3.1.42 palmitoyl-CoA + dihydroxyacetone phosphate reaction in phosphatidic acid biosynthesis Oryctolagus cuniculus CoA + monopalmitoyldihydroxyacetone phosphate
-
 ?
2.3.1.42 palmitoyl-CoA + dihydroxyacetone phosphate peroxisomal enzyme involved in ether lipid biosynthesis Oryctolagus cuniculus CoA + monopalmitoyldihydroxyacetone phosphate
-
 ?