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Literature summary extracted from

  • Joshi, V.C.
    Mechanism of malonyl-coenzyme A-acyl carrier protein transacylase (1972), Biochem. J., 128, 43P-44P.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.39 acetyl-CoA competitive to malonyl-CoA Escherichia coli
2.3.1.39 CoA
-
 Escherichia coli
2.3.1.39 p-toluenesulfonyl fluoride strong inhibitor Escherichia coli
2.3.1.39 phenylmethanesulfonyl fluoride
-
 Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.39 35000
-
 x * 35000, SDS-PAGE Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.39 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.39
-
 Escherichia coli

Reaction

EC Number Reaction Comment Organism Reaction ID
2.3.1.39 malonyl-CoA + an [acyl-carrier protein] = CoA + a malonyl-[acyl-carrier protein] mechanism, formation of a malonyl-enzyme intermediate Escherichia coli
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.39 malonyl-CoA + acyl-carrier protein acetyl-CoA cannot replace malonyl-CoA Escherichia coli CoA + malonyl-[acyl-carrier protein]
-
 ?
2.3.1.39 malonyl-CoA + acyl-carrier protein the enzyme is very specific for the malonyl group Escherichia coli CoA + malonyl-[acyl-carrier protein]
-
 ?
2.3.1.39 malonyl-CoA + N-(N-acetyl-beta-alanyl)cysteamine
-
 Escherichia coli CoA + N-(N-acetyl-beta-alanyl)-S-malonylcysteamine
-
 ?
2.3.1.39 malonyl-CoA + N-acetylcysteamine
-
 Escherichia coli CoA + N-acetyl-S-malonylcysteamine
-
 ?
2.3.1.39 malonyl-CoA + pantetheine
-
 Escherichia coli malonyl-pantetheine + CoA
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.39 ? x * 35000, SDS-PAGE Escherichia coli