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Literature summary extracted from

  • Yubisui, T.; Yoneyama, Y.
    delta-Aminolevulinic acid synthetase of Rhodopseudomonas spheroides: purification and properties of the enzyme (1972), Arch. Biochem. Biophys., 150, 77-85.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.37 EDTA required Cereibacter sphaeroides

General Stability

EC Number General Stability Organism
2.3.1.37 freezing and thawing: precipitation and loss of activity Cereibacter sphaeroides

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.37 2-mercaptoethanol
-
 Cereibacter sphaeroides
2.3.1.37 Cu2+ at low concentration Cereibacter sphaeroides
2.3.1.37 Fe2+
-
 Cereibacter sphaeroides
2.3.1.37 Fe3+ slight Cereibacter sphaeroides
2.3.1.37 hemin
-
 Cereibacter sphaeroides
2.3.1.37 Hg2+ 2-mercaptoethanol protects partly Cereibacter sphaeroides
2.3.1.37 iodoacetamide
-
 Cereibacter sphaeroides
2.3.1.37 Mg-protoporphyrin
-
 Cereibacter sphaeroides
2.3.1.37 N-ethylmaleimide 2-mercaptoethanol protect Cereibacter sphaeroides
2.3.1.37 p-chloromercuribenzoate 2-mercaptoethanol protect partly Cereibacter sphaeroides
2.3.1.37 protoporphyrin weak Cereibacter sphaeroides
2.3.1.37 Zn2+
-
 Cereibacter sphaeroides

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.37 61000
-
 gel filtration Cereibacter sphaeroides

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.37 Cereibacter sphaeroides
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.37
-
 Cereibacter sphaeroides

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.37 0.558
-
 purified enzyme Cereibacter sphaeroides

Storage Stability

EC Number Storage Stability Organism
2.3.1.37 5°C, 50 mM phosphate buffer, pH 7.2, 10 mM 2-mercaptoethanol, 20% loss of activity after 1 week Cereibacter sphaeroides

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.37 succinyl-CoA + glycine
-
 Cereibacter sphaeroides 5-aminolevulinate + CoA + CO2
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.37 7.2
-
-
 Cereibacter sphaeroides

Cofactor

EC Number Cofactor Comment Organism Structure
2.3.1.37 pyridoxal 5'-phosphate
-
 Cereibacter sphaeroides