BRENDA - Enzyme Database show

Hemin feedback inhibition at reticulocyte delta-aminolevulinic acid synthetase and delta-aminolevulinic acid dehydratase

Ibrahim, N.G.; Gruenspecht, N.R.; Freedman, M.L.; Biochem. Biophys. Res. Commun. 80, 722-728 (1978)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.3.1.37
hemin
feed-back inhibition
Oryctolagus cuniculus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.3.1.37
cytosol
-
Oryctolagus cuniculus
5829
-
2.3.1.37
mitochondrion
-
Oryctolagus cuniculus
5739
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.3.1.37
Oryctolagus cuniculus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.3.1.37
reticulocyte
-
Oryctolagus cuniculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.3.1.37
succinyl-CoA + glycine
-
486827
Oryctolagus cuniculus
5-aminolevulinate + CoA + CO2
-
486827
Oryctolagus cuniculus
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
2.3.1.37
pyridoxal 5'-phosphate
-
Oryctolagus cuniculus
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
2.3.1.37
pyridoxal 5'-phosphate
-
Oryctolagus cuniculus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.3.1.37
hemin
feed-back inhibition
Oryctolagus cuniculus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.3.1.37
cytosol
-
Oryctolagus cuniculus
5829
-
2.3.1.37
mitochondrion
-
Oryctolagus cuniculus
5739
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.3.1.37
reticulocyte
-
Oryctolagus cuniculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.3.1.37
succinyl-CoA + glycine
-
486827
Oryctolagus cuniculus
5-aminolevulinate + CoA + CO2
-
486827
Oryctolagus cuniculus
?