EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.26 | expression in enzyme-deficient mutant chinese hamster ovary cells | Homo sapiens |
2.3.1.26 | expression of an antisense cDNA in HepG2 cells | Homo sapiens |
2.3.1.26 | sequence analysis and human cDNA clones indicate homology to liver carboxylesterase | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.3.1.26 | microsome | - |
Homo sapiens | - |
- |
2.3.1.26 | microsome | - |
Sus scrofa | - |
- |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.3.1.26 | 58000 | - |
x * 58000, SDS-PAGE | Sus scrofa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.26 | long-chain fatty acyl-CoA + cholesterol | Sus scrofa | - |
CoA + cholesteryl long-chain fatty acyl ester | - |
? | |
2.3.1.26 | long-chain fatty acyl-CoA + cholesterol | Homo sapiens | the enzyme is relevant for cellular cholesterol esterification in vivo, the regulation in human mononuclear phagocytes indicates that the enzyme is also involved in foam cell formation during early atherogenesis | CoA + cholesteryl long-chain fatty acyl ester | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.26 | Homo sapiens | - |
- |
- |
2.3.1.26 | Sus scrofa | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.3.1.26 | based on solubilization in CHAPS, preparative free-flow isotachophoresis, and further separation of the protein showing enzyme activity by preparative free-flow IEF, followed by removal of nonglycosylated proteins by ConA-affinity chromatography and preparative SDS-PAGE | Sus scrofa |
EC Number | Renatured (Comment) | Organism |
---|---|---|
2.3.1.26 | reconstitution with liposomes | Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.3.1.26 | liver | - |
Homo sapiens | - |
2.3.1.26 | liver | - |
Sus scrofa | - |
2.3.1.26 | macrophage | - |
Homo sapiens | - |
2.3.1.26 | monocyte | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.26 | long-chain fatty acyl-CoA + cholesterol | - |
Sus scrofa | CoA + cholesteryl long-chain fatty acyl ester | - |
? | |
2.3.1.26 | long-chain fatty acyl-CoA + cholesterol | the enzyme is relevant for cellular cholesterol esterification in vivo, the regulation in human mononuclear phagocytes indicates that the enzyme is also involved in foam cell formation during early atherogenesis | Homo sapiens | CoA + cholesteryl long-chain fatty acyl ester | - |
? | |
2.3.1.26 | oleoyl-CoA + cholesterol | - |
Homo sapiens | CoA + cholesteryl oleate | - |
? | |
2.3.1.26 | oleoyl-CoA + cholesterol | - |
Sus scrofa | CoA + cholesteryl oleate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.3.1.26 | ? | x * 58000, SDS-PAGE | Sus scrofa |