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Literature summary extracted from

  • Doolittle, G.M.; Chang, T.Y.
    Acyl-CoA:cholesterol acyltransferase in Chinese hamster ovary cells. Enzyme activity determined after reconstitution in phospholipid/cholesterol liposomes (1982), Biochim. Biophys. Acta, 713, 529-537.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.26 low density lipoprotein increase of activity Cricetulus griseus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.26 endoplasmic reticulum
-
 Cricetulus griseus 5783
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.26 Cricetulus griseus
-
-
-

Renatured (Commentary)

EC Number Renatured (Comment) Organism
2.3.1.26 solubilization of enzyme activity by deoxycholate, reconstitution of the solubilized activity into liposome of known cholesterol and phospholipid content by employing a cholate dialysis procedure Cricetulus griseus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.26 CHO cell CHO cells, cultured cells Cricetulus griseus
-
2.3.1.26 peritoneal macrophage
-
 Cricetulus griseus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.26 additional information
-
 comparison of enzyme activities of cells grown in fetal calf serum medium and in delipidated serum medium Cricetulus griseus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.26 acyl-CoA + cholesterol
-
 Cricetulus griseus CoA + cholesterol ester
-
 ?