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Literature summary extracted from

  • Miller, L.R.; Needleman, D.H.; Brabson, J.S.; Wang, K.S.; Schroepfer, G.J.
    5alpha-Cholest-8(14)-en-3beta-ol-15-one. A competitive substrate for acyl coenzyme A: cholesterol acyl transferase (1987), Biochem. Biophys. Res. Commun., 148, 934-940.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.26 5alpha-Cholest-8(14)-en-3beta-ol-15-one inhibits the esterification of cholesterol Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.26 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.26 Rattus norvegicus
-
 male Sprague-Dawley strain
-
2.3.1.26 Rattus norvegicus male Sprague-Dawley
-
 male Sprague-Dawley strain
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.26 intestine
-
 Rattus norvegicus
-
2.3.1.26 jejunum
-
 Rattus norvegicus
-
2.3.1.26 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.26 acyl-CoA + cholesterol
-
 Rattus norvegicus CoA + cholesterol ester
-
 ?
2.3.1.26 acyl-CoA + cholesterol
-
 Rattus norvegicus male Sprague-Dawley CoA + cholesterol ester
-
 ?
2.3.1.26 oleoyl-CoA + 5alpha-cholest-8(14)-en-3beta-ol-15-one
-
 Rattus norvegicus CoA + 15-oxo-5alpha-cholest-8(14)-en-3beta-yl (9Z)-octadec-9-enoate
-
 ?
2.3.1.26 oleoyl-CoA + 5alpha-cholest-8(14)-en-3beta-ol-15-one
-
 Rattus norvegicus male Sprague-Dawley CoA + 15-oxo-5alpha-cholest-8(14)-en-3beta-yl (9Z)-octadec-9-enoate
-
 ?
2.3.1.26 oleoyl-CoA + 5alpha-cholest-8(14)-en-3beta-ol-15-one
-
 Rattus norvegicus CoA + oleate ester of 5alpha-cholest-8(14)-en-3beta-ol-15-one
-
 ?
2.3.1.26 oleoyl-CoA + 5alpha-cholest-8(14)-en-3beta-ol-15-one
-
 Rattus norvegicus male Sprague-Dawley CoA + oleate ester of 5alpha-cholest-8(14)-en-3beta-ol-15-one
-
 ?
2.3.1.26 oleoyl-CoA + cholesterol
-
 Rattus norvegicus CoA + cholesteryl oleate
-
 ?
2.3.1.26 oleoyl-CoA + cholesterol
-
 Rattus norvegicus male Sprague-Dawley CoA + cholesteryl oleate
-
 ?