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Literature summary extracted from

  • Arthur, G.; Page, L.L.; Zaborniak, C.L.; Choy, P.C.
    The acylation of lysophosphoradylglycerocholines in guinea-pig heart mitochondria (1987), Biochem. J., 242, 171-175.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.23 1-alkenylglycerophosphocholine
-
 Cavia porcellus
2.3.1.23 Ca2+ 10 mM, weak inhibition Cavia porcellus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.23 0.0124
-
 1-acyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus
2.3.1.23 0.0124
-
 1-acyl-sn-glycero-3-phosphocholine enzyme from heart mitochondria Cavia porcellus
2.3.1.23 0.092
-
 1-alkenyl-sn-glycero-3-phosphocholine enzyme from heart mitochondria Cavia porcellus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.23 mitochondrion
-
 Cavia porcellus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.23 Cavia porcellus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.23 heart
-
 Cavia porcellus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 linoleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine only acyl donor of the mitochondrial enzyme, 1-acyl-sn-glycero-3-phosphocholine and 1-alkenyl-sn-glycero-3-phosphocholine can act as acyl acceptors Cavia porcellus CoA + 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 linoleoyl-CoA + 1-alkenyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.23 25
-
 assay at Cavia porcellus

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.3.1.23 55
-
 70% loss of activity after 3 min, t1/2 about 2 min Cavia porcellus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.23 7
-
 1-acyl-sn-glycero-3-phosphocholine and 1-alkenyl-sn-glycero-3-phosphocholine acyltransferase activities Cavia porcellus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.3.1.23 5 10 approx. half-maximal activity at pH 5.0 and 10.0 Cavia porcellus