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Literature summary extracted from

  • Sanjanwala, M.; Sun, G.Y.; Cutrera, M.A.; MacQuarrie, R.
    Acylation of lysophosphatidylcholine in bovine heart muscle microsomes: purification and kinetic properties of acyl-CoA: 1-acyl-sn-glycero-3-phosphocholine O-acyltransferase (1988), Arch. Biochem. Biophys., 265, 476-483.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.23 additional information
-
 additional information kinetic study Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.23 microsome
-
 Bos taurus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.23 64000
-
 x * 64000, heart enzyme, SDS-PAGE Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine Bos taurus determines composition of phosphocholine in myocardium CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.23 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.23 reactive blue 2-agarose, DEAE-Cellulose, Matrex green A Bos taurus
2.3.1.23 solubilized with CHAPS Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.23 heart myocardium Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.23 13.33
-
 acyl donor oleoyl-CoA Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine determines composition of phosphocholine in myocardium Bos taurus CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.23 decanoyl-CoA + 1-palmitoyl-sn-glycero-3-phosphocholine highest activity with 1-palmitoyl-sn-glycero-3-phosphocholine as acceptor, preferred acyl donors in descending order: decanoyl-CoA, oleoyl-CoA, arachidonoyl-CoA, stearoyl-CoA, linolenoyl-CoA, dodecanoyl-CoA, palmitoyl-CoA Bos taurus CoA + 1-palmitoyl-2-decanoyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.23 oleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine best acyl donor Bos taurus CoA + 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine
-
 r

Subunits

EC Number Subunits Comment Organism
2.3.1.23 ? x * 64000, heart enzyme, SDS-PAGE Bos taurus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.23 37
-
-
 Bos taurus