EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.22 | bovine serum albumin | stimulates | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.22 | 2,4,6-Trinitrobenzene sulfonic acid | - |
Rattus norvegicus | |
2.3.1.22 | CaCl2 | 12.5 mM, 20-30% inhibition | Rattus norvegicus | |
2.3.1.22 | HgCl2 | 0.5 mM, complete inhibition | Rattus norvegicus | |
2.3.1.22 | KI | 300 mM, 30% inhibition | Rattus norvegicus | |
2.3.1.22 | MnCl2 | 10 mM, 18-25%; 2.5-5 mM, 40% inhibition of enzymne from neonatal liver | Rattus norvegicus | |
2.3.1.22 | NEM | 2 mM, 12% inhibition | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.3.1.22 | microsome | - |
Rattus norvegicus | - |
- |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.22 | Mn2+ | 2.5-5 mM, stimulates 160%, enzyme from adult liver | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.22 | acyl-CoA + sn-2-monoacylglycerol | Rattus norvegicus | the enzyme is developmentally expressed, associated with physiological periods characterized by high rates of lipolysis and depends on fatty acids for energy production. During these periods the enzyme may help to retain essential fatty acids selectively | CoA + diacylglycerol | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.22 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.3.1.22 | liver | adult and neonatal, enhanced expression in diabetes | Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.22 | acyl-CoA + sn-2-monoacylglycerol | the enzyme is developmentally expressed, associated with physiological periods characterized by high rates of lipolysis and depends on fatty acids for energy production. During these periods the enzyme may help to retain essential fatty acids selectively | Rattus norvegicus | CoA + diacylglycerol | - |
? | |
2.3.1.22 | palmitoyl-CoA + sn-2-monooleoylglycerol | - |
Rattus norvegicus | CoA + 1(3)-palmitoyl-2-oleoylglycerol | - |
? |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.3.1.22 | 51 | - |
after microsomes from adult liver are incubated for 13 min, they retain 44% of the control activity. After 13.5 min of heating, neonatal liver microsomes retain 90% of the control activity | Rattus norvegicus |
2.3.1.22 | 56 | - |
after microsomes from adult liver are incubated for 13 min, they retain 7% of the control activity. After 13.5 min of heating, neonatal liver microsomes retain 57% of the control activity | Rattus norvegicus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.3.1.22 | 7 | - |
- |
Rattus norvegicus |