Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Yen, C.L.E.; Stone, S.J.; Cases, S.; Zhou, P.; Farese, R.V., Jr.
    Identification of a gene encoding MGAT1, a monoacylglycerol acyltransferase (2002), Proc. Natl. Acad. Sci. USA, 99, 8512-8517.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.22 expression of MGAT1 cDNA in Spodoptera frugiperda cells Mus musculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.22 33000
-
 x * 33000, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.22 acyl-CoA + sn-2-monoacylglycerol Mus musculus in the intestine the enzyme plays a major role in the absorption of dietary fat because resynthesis of triacylglycerol is required for the assembly of lipoproteins that transport absorbed fat to other tissues CoA + diacylglycerol
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.22 Mus musculus Q91ZV4
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.22 brown adipose tissue MGAT1 Mus musculus
-
2.3.1.22 kidney
-
 Mus musculus
-
2.3.1.22 liver MGAT1 Mus musculus
-
2.3.1.22 stomach
-
 Mus musculus
-
2.3.1.22 white adipose tissue MGAT1 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.22 acyl-CoA + sn-2-monoacylglycerol in the intestine the enzyme plays a major role in the absorption of dietary fat because resynthesis of triacylglycerol is required for the assembly of lipoproteins that transport absorbed fat to other tissues Mus musculus CoA + diacylglycerol
-
 ?
2.3.1.22 arachidonoyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + 1-arachidonoyl-2-oleoylglycerol
-
 ?
2.3.1.22 arachidoyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + 1-arachidoyl-2-oleoylglycerol
-
 ?
2.3.1.22 lauroyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + 1-lauroyl-2-oleoylglycerol
-
 ?
2.3.1.22 linoleoyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + 1-linoleoyl-2-oleoylglycerol
-
 ?
2.3.1.22 n-octanoyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + 1-octanoyl-2-oleoylglycerol
-
 ?
2.3.1.22 oleoyl-CoA + sn-1-monooleoylglycerol
-
 Mus musculus CoA + sn-1,3-dioleoylglycerol
-
 ?
2.3.1.22 oleoyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + sn-1,2(2,3)-dioleoylglycerol
-
 ?
2.3.1.22 oleoyl-CoA + sn-3-monostearoylglycerol
-
 Mus musculus CoA + 1-oleoyl-3-stearoylglycerol
-
 ?
2.3.1.22 palmitoyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + 1(3)-palmitoyl-2-oleoylglycerol
-
 ?
2.3.1.22 stearoyl-CoA + sn-2-monooleoylglycerol
-
 Mus musculus CoA + 1-stearoyl-2-oleolyglycerol
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.22 ? x * 33000, SDS-PAGE Mus musculus