BRENDA - Enzyme Database

Identification of a gene encoding MGAT1, a monoacylglycerol acyltransferase

Yen, C.L.E.; Stone, S.J.; Cases, S.; Zhou, P.; Farese, R.V., Jr.; Proc. Natl. Acad. Sci. USA 99, 8512-8517 (2002) View publication on PubMedView publication on EuropePMC

Data extracted from this reference:

Cloned(Commentary)
EC Number
Cloned (Commentary)
Organism
2.3.1.22
expression of MGAT1 cDNA in Spodoptera frugiperda cells
Mus musculus
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.3.1.22
33000
-
x * 33000, SDS-PAGE
Mus musculus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
2.3.1.22
acyl-CoA + sn-2-monoacylglycerol
Mus musculus
in the intestine the enzyme plays a major role in the absorption of dietary fat because resynthesis of triacylglycerol is required for the assembly of lipoproteins that transport absorbed fat to other tissues
CoA + diacylglycerol
-
-
?
Organism
EC Number
Organism
UniProt
Commentary
Textmining
2.3.1.22
Mus musculus
Q91ZV4
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.3.1.22
brown adipose tissue
MGAT1
Mus musculus
-
2.3.1.22
kidney
-
Mus musculus
-
2.3.1.22
liver
MGAT1
Mus musculus
-
2.3.1.22
stomach
-
Mus musculus
-
2.3.1.22
white adipose tissue
MGAT1
Mus musculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
2.3.1.22
acyl-CoA + sn-2-monoacylglycerol
in the intestine the enzyme plays a major role in the absorption of dietary fat because resynthesis of triacylglycerol is required for the assembly of lipoproteins that transport absorbed fat to other tissues
486605
Mus musculus
CoA + diacylglycerol
-
-
-
?
2.3.1.22
arachidonoyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + 1-arachidonoyl-2-oleoylglycerol
-
-
-
?
2.3.1.22
arachidoyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + 1-arachidoyl-2-oleoylglycerol
-
-
-
?
2.3.1.22
lauroyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + 1-lauroyl-2-oleoylglycerol
-
-
-
?
2.3.1.22
linoleoyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + 1-linoleoyl-2-oleoylglycerol
-
-
-
?
2.3.1.22
n-octanoyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + 1-octanoyl-2-oleoylglycerol
-
-
-
?
2.3.1.22
oleoyl-CoA + sn-1-monooleoylglycerol
-
486605
Mus musculus
CoA + sn-1,3-dioleoylglycerol
-
486605
Mus musculus
?
2.3.1.22
oleoyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + sn-1,2(2,3)-dioleoylglycerol
-
486605
Mus musculus
?
2.3.1.22
oleoyl-CoA + sn-3-monostearoylglycerol
-
486605
Mus musculus
CoA + 1-oleoyl-3-stearoylglycerol
-
486605
Mus musculus
?
2.3.1.22
palmitoyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + 1(3)-palmitoyl-2-oleoylglycerol
-
-
-
?
2.3.1.22
stearoyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + 1-stearoyl-2-oleolyglycerol
-
-
-
?
Subunits
EC Number
Subunits
Commentary
Organism
2.3.1.22
?
x * 33000, SDS-PAGE
Mus musculus
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
2.3.1.22
expression of MGAT1 cDNA in Spodoptera frugiperda cells
Mus musculus
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.3.1.22
33000
-
x * 33000, SDS-PAGE
Mus musculus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
2.3.1.22
acyl-CoA + sn-2-monoacylglycerol
Mus musculus
in the intestine the enzyme plays a major role in the absorption of dietary fat because resynthesis of triacylglycerol is required for the assembly of lipoproteins that transport absorbed fat to other tissues
CoA + diacylglycerol
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.3.1.22
brown adipose tissue
MGAT1
Mus musculus
-
2.3.1.22
kidney
-
Mus musculus
-
2.3.1.22
liver
MGAT1
Mus musculus
-
2.3.1.22
stomach
-
Mus musculus
-
2.3.1.22
white adipose tissue
MGAT1
Mus musculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
2.3.1.22
acyl-CoA + sn-2-monoacylglycerol
in the intestine the enzyme plays a major role in the absorption of dietary fat because resynthesis of triacylglycerol is required for the assembly of lipoproteins that transport absorbed fat to other tissues
486605
Mus musculus
CoA + diacylglycerol
-
-
-
?
2.3.1.22
arachidonoyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + 1-arachidonoyl-2-oleoylglycerol
-
-
-
?
2.3.1.22
arachidoyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + 1-arachidoyl-2-oleoylglycerol
-
-
-
?
2.3.1.22
lauroyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + 1-lauroyl-2-oleoylglycerol
-
-
-
?
2.3.1.22
linoleoyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + 1-linoleoyl-2-oleoylglycerol
-
-
-
?
2.3.1.22
n-octanoyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + 1-octanoyl-2-oleoylglycerol
-
-
-
?
2.3.1.22
oleoyl-CoA + sn-1-monooleoylglycerol
-
486605
Mus musculus
CoA + sn-1,3-dioleoylglycerol
-
486605
Mus musculus
?
2.3.1.22
oleoyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + sn-1,2(2,3)-dioleoylglycerol
-
486605
Mus musculus
?
2.3.1.22
oleoyl-CoA + sn-3-monostearoylglycerol
-
486605
Mus musculus
CoA + 1-oleoyl-3-stearoylglycerol
-
486605
Mus musculus
?
2.3.1.22
palmitoyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + 1(3)-palmitoyl-2-oleoylglycerol
-
-
-
?
2.3.1.22
stearoyl-CoA + sn-2-monooleoylglycerol
-
486605
Mus musculus
CoA + 1-stearoyl-2-oleolyglycerol
-
-
-
?
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
2.3.1.22
?
x * 33000, SDS-PAGE
Mus musculus