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Literature summary extracted from

  • Kopec, B.; Fritz, I.B.
    Comparison of properties of carnitine palmitoyltransferase I with those of carnitine palmitoyltransferase II, and preparation of antibodies to carnitine palmitoyltransferases (1973), J. Biol. Chem., 248, 4069-4074.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.21 Short chain-length fatty acylcarnitine derivatives
-
 Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.21 150000
-
 CPT I and II, gel filtration Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine Rattus norvegicus
-
 CoA + L-acylcarnitine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.21 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.21 CPT II, partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.21 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-acylcarnitine
-
 ?
2.3.1.21 acyl-CoA + L-carnitine CPT II shows greater chain-length substrate specificity for transfer of long chain fatty acyl groups from (-)-acylcarnitine derivatives to CoA-SH with greatest activity being obtained in the transfer of stearoyl and palmitoyl groups Rattus norvegicus CoA + L-acylcarnitine
-
 ?
2.3.1.21 acyl-CoA + L-carnitine CPT II requires preincubation with CoA-SH for manifestation of catalytic activity Rattus norvegicus CoA + L-acylcarnitine
-
 ?
2.3.1.21 acyl-CoA + L-carnitine isozyme CPT II catalyzes the reaction only in the direction towards long-chain fatty acyl-CoA formation, CPT I catalyzes reaction in both directions Rattus norvegicus CoA + L-acylcarnitine
-
 ?
2.3.1.21 palmitoyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-palmitoylcarnitine
-
 ?
2.3.1.21 palmitoyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-palmitoylcarnitine
-
 r