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Literature summary extracted from

  • Chung, C.H.; Woldegiorgis, G.; Dai, G.; Shrago, E.; Bieber, L.L.
    Conferral of malonyl coenzyme A sensitivity to purified rat heart mitochondrial carnitine palmitoyltransferase (1992), Biochemistry, 31, 9777-9783.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.21 malonyl-CoA mitochondrial isozyme CPT I, sensitivity against malonyl-CoA is mediated by a 86 kDa malonyl-CoA binding protein complexed with CPT and other proteins of the beta-oxidation, detergent and salt sensitive Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.21 mitochondrion
-
 Rattus norvegicus 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.21 additional information
-
 mitochondrial enzyme, 86 kDa malonyl-CoA binding protein complexed with CPT and other proteins of the beta-oxidation Rattus norvegicus
2.3.1.21 86000
-
 86000 MW malonyl-CoA binding protein is a regulatory subunit of the carnitine palmitoyltransferase complex Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine Rattus norvegicus
-
 CoA + L-acylcarnitine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.21 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.21 heart
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-acylcarnitine
-
 ?
2.3.1.21 decanoyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-decanoylcarnitine
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.21 More 86000 MW malonyl-CoA binding protein is a regulatory subunit of the carnitine palmitoyltransferase complex Rattus norvegicus