Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Halperin, M.L.; Pande, S.V.
    Fatty acyl group transport into mitochondria: carnitine palmitoyl transferases EC 2.3.1.23 and the carnitine-acylcarnitine translocase (1979), Methods Enzymol., 56, 368-378.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.21 0.0055
-
 CoA
-
 Bos taurus
2.3.1.21 0.018
-
 palmitoyl-CoA
-
 Bos taurus
2.3.1.21 0.14
-
 L-palmitoylcarnitine
-
 Bos taurus
2.3.1.21 0.45
-
 L-carnitine
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.21 mitochondrial inner membrane enzyme is present on both sides of the inner membrane, not on the outer membrane Rattus norvegicus 5743
-
2.3.1.21 mitochondrial inner membrane enzyme is present on both sides of the inner membrane, not on the outer membrane Bos taurus 5743
-
2.3.1.21 mitochondrion
-
 Rattus norvegicus 5739
-
2.3.1.21 mitochondrion
-
 Bos taurus 5739
-
2.3.1.21 additional information transport mechanism for acylcaritine and carnitine through the mitochondrial inner membrane Rattus norvegicus
-
-
2.3.1.21 additional information transport mechanism for acylcaritine and carnitine through the mitochondrial inner membrane Bos taurus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine Rattus norvegicus
-
 CoA + L-acylcarnitine
-
 ?
2.3.1.21 acyl-CoA + L-carnitine Bos taurus
-
 CoA + L-acylcarnitine
-
 ?
2.3.1.21 additional information Rattus norvegicus participates in fatty acyl group transport into mitochondria ?
-
 ?
2.3.1.21 additional information Bos taurus participates in fatty acyl group transport into mitochondria ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.21 Bos taurus
-
 calf
-
2.3.1.21 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.21 calf liver Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.21 heart
-
 Rattus norvegicus
-
2.3.1.21 heart
-
 Bos taurus
-
2.3.1.21 liver
-
 Rattus norvegicus
-
2.3.1.21 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-acylcarnitine
-
 ?
2.3.1.21 acyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-acylcarnitine
-
 r
2.3.1.21 acyl-CoA + L-carnitine
-
 Bos taurus CoA + L-acylcarnitine
-
 ?
2.3.1.21 acyl-CoA + L-carnitine
-
 Bos taurus CoA + L-acylcarnitine reverse reaction with palmitoylcarnitine r
2.3.1.21 acyl-CoA + L-carnitine
-
 Bos taurus CoA + L-acylcarnitine reverse reaction: myristoylcarnitine r
2.3.1.21 additional information participates in fatty acyl group transport into mitochondria Rattus norvegicus ?
-
 ?
2.3.1.21 additional information participates in fatty acyl group transport into mitochondria Bos taurus ?
-
 ?
2.3.1.21 myristoyl-CoA + L-carnitine
-
 Bos taurus CoA + L-myristoylcarnitine
-
 ?
2.3.1.21 palmitoyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-palmitoylcarnitine
-
 r
2.3.1.21 palmitoyl-CoA + L-carnitine
-
 Bos taurus CoA + L-palmitoylcarnitine
-
 r

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.21 7 8.2
-
 Bos taurus