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Literature summary extracted from

  • Parthasarathy, S.; Murari, R.; Crilly, K.S.; Baumann, W.J.
    Modulation of diacylglycerol acyltransferase by lysophosphatidylcholine and related monochain phospholipids (1981), Biochim. Biophys. Acta, 664, 249-254.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.20 1-acyl-sn-glycero-3-phosphocholine activation, at low concentrations, inhibition above 0.2 mM Rattus norvegicus
2.3.1.20 1-acyl-sn-glycero-3-phosphoethanolamine activation, to a lesser extent Rattus norvegicus
2.3.1.20 1-O-Hexadecylpropanediol-3-phosphocholine activation, low concentration, inhibitory at high concentration Rattus norvegicus
2.3.1.20 lysophosphatidylcholine activation at low concentrations, optimum at 0.075 mM, inhibitory above 0.2 mM Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.20 1-acyl-sn-glycero-3-phosphocholine activation, at low concentrations, inhibition above 0.2 mM Rattus norvegicus
2.3.1.20 1-O-Hexadecylpropanediol-3-phosphocholine activation, low concentration, inhibitory at high concentration Rattus norvegicus
2.3.1.20 lysophosphatidylcholine activation at low concentrations, optimum at 0.075 mM, inhibitory above 0.2 mM Rattus norvegicus
2.3.1.20 sodium taurocholate
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.20 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.20 Rattus norvegicus
-
 Sprague-Dawley
-
2.3.1.20 Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.20 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.20 acyl-CoA + 1,2-diacylglycerol
-
 Rattus norvegicus CoA + triacylglycerol
-
 ?
2.3.1.20 acyl-CoA + 1,2-diacylglycerol
-
 Rattus norvegicus Sprague-Dawley CoA + triacylglycerol
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.20 additional information
-
 assay at various temperatures from 24°C to 40°C Rattus norvegicus