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Literature summary extracted from

  • Middleton, B.
    3-Ketoacyl-CoA thiolase of mammalian tissues (1975), Methods Enzymol., 35 B, 128-136.
No PubMed abstract available

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.16 0.01
-
 acetoacetyl-CoA
-
 Rattus norvegicus
2.3.1.16 0.018
-
 CoA
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.16 mitochondrion
-
 Rattus norvegicus 5739
-
2.3.1.16 mitochondrion
-
 Sus scrofa 5739
-
2.3.1.16 mitochondrion
-
 Bos taurus 5739
-
2.3.1.16 mitochondrion
-
 Ovis aries 5739
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.16 Bos taurus
-
-
-
2.3.1.16 Ovis aries
-
 male
-
2.3.1.16 Rattus norvegicus
-
-
-
2.3.1.16 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.16 general method for separation, quantitation and partial purification Bos taurus
2.3.1.16 general method for separation, quantitation and partial purification Ovis aries

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.16 brain
-
 Rattus norvegicus
-
2.3.1.16 heart
-
 Rattus norvegicus
-
2.3.1.16 heart
-
 Sus scrofa
-
2.3.1.16 heart
-
 Bos taurus
-
2.3.1.16 kidney
-
 Rattus norvegicus
-
2.3.1.16 liver
-
 Rattus norvegicus
-
2.3.1.16 liver
-
 Sus scrofa
-
2.3.1.16 liver
-
 Bos taurus
-
2.3.1.16 semen
-
 Ovis aries
-

Storage Stability

EC Number Storage Stability Organism
2.3.1.16 -20°C, glycerol, several weeks Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.16 CoA + 3-oxoacyl-CoA
-
 Rattus norvegicus acyl-CoA + acetyl-CoA
-
 r
2.3.1.16 CoA + 3-oxoacyl-CoA
-
 Sus scrofa acyl-CoA + acetyl-CoA
-
 r
2.3.1.16 CoA + 3-oxoacyl-CoA
-
 Bos taurus acyl-CoA + acetyl-CoA
-
 r
2.3.1.16 CoA + 3-oxoacyl-CoA
-
 Ovis aries acyl-CoA + acetyl-CoA
-
 ?
2.3.1.16 CoA + 3-oxohexanoyl-CoA highest activity with 3-oxohexanoyl-CoA Rattus norvegicus acetyl-CoA + butanoyl-CoA
-
 r
2.3.1.16 CoA + 3-oxohexanoyl-CoA highest activity with 3-oxohexanoyl-CoA Sus scrofa acetyl-CoA + butanoyl-CoA
-
 r
2.3.1.16 CoA + 3-oxohexanoyl-CoA highest activity with 3-oxohexanoyl-CoA Bos taurus acetyl-CoA + butanoyl-CoA
-
 r
2.3.1.16 CoA + 3-oxohexanoyl-CoA highest activity with 3-oxohexanoyl-CoA Ovis aries acetyl-CoA + butanoyl-CoA
-
 ?
2.3.1.16 CoA + 3-oxopalmitoyl-CoA
-
 Rattus norvegicus acetyl-CoA + tetradecanoyl-CoA
-
 ?
2.3.1.16 CoA + 3-oxopalmitoyl-CoA
-
 Sus scrofa acetyl-CoA + tetradecanoyl-CoA
-
 ?
2.3.1.16 CoA + 3-oxopalmitoyl-CoA
-
 Bos taurus acetyl-CoA + tetradecanoyl-CoA
-
 ?
2.3.1.16 CoA + acetoacetyl-CoA
-
 Rattus norvegicus acetyl-CoA + acetyl-CoA
-
 r
2.3.1.16 CoA + acetoacetyl-CoA
-
 Sus scrofa acetyl-CoA + acetyl-CoA
-
 r
2.3.1.16 CoA + acetoacetyl-CoA
-
 Bos taurus acetyl-CoA + acetyl-CoA
-
 r
2.3.1.16 additional information 3-oxoacyl-CoA homologues from acetoacetyl to 3-oxopalmitoyl-CoA Rattus norvegicus ?
-
 ?
2.3.1.16 additional information 3-oxoacyl-CoA homologues from acetoacetyl to 3-oxopalmitoyl-CoA Sus scrofa ?
-
 ?
2.3.1.16 additional information 3-oxoacyl-CoA homologues from acetoacetyl to 3-oxopalmitoyl-CoA Bos taurus ?
-
 ?
2.3.1.16 additional information 3-oxoacyl-CoA homologues from acetoacetyl to 3-oxopalmitoyl-CoA Ovis aries ?
-
 ?