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Literature summary extracted from

  • Junghanns, K.T.; Kneusel, R.E.; Groger, D.; Matern, U.
    Differential regulation and distribution of acridone synthase in Ruta graveolens (1998), Phytochemistry, 49, 403-411.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.159 additional information induced activity by addition of crude elicitors from the cell wall of Phytophthora megasperma f. sp. glycinea, syn. Phytophthora sojae Ruta graveolens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.159 additional information light irradiation decreases activity Ruta graveolens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.159 malonyl-CoA + N-methylanthraniloyl-CoA Ruta graveolens activity is increased upon treatment with crude elicitors from the cell wall of Phytophthora megasperma f. sp. glycinea, syn. Phytophthora sojae, and decreased upon light irradiation CoA + 1,3-dihydroxy-N-methylacridone + CO2
-
 ?
2.3.1.159 malonyl-CoA + N-methylanthraniloyl-CoA Ruta graveolens involved in the biosynthesis of all acridone alkaloids CoA + 1,3-dihydroxy-N-methylacridone + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.159 Ruta graveolens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.159 cell suspension culture strain R-20 Ruta graveolens
-
2.3.1.159 hypocotyl endodermis and vascular tissue, mRNA and protein Ruta graveolens
-
2.3.1.159 root adjacent to the rhizodermis, mRNA and protein Ruta graveolens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.159 malonyl-CoA + N-methylanthraniloyl-CoA
-
 Ruta graveolens CoA + 1,3-dihydroxy-N-methylacridone + CO2
-
 ?
2.3.1.159 malonyl-CoA + N-methylanthraniloyl-CoA activity is increased upon treatment with crude elicitors from the cell wall of Phytophthora megasperma f. sp. glycinea, syn. Phytophthora sojae, and decreased upon light irradiation Ruta graveolens CoA + 1,3-dihydroxy-N-methylacridone + CO2
-
 ?
2.3.1.159 malonyl-CoA + N-methylanthraniloyl-CoA involved in the biosynthesis of all acridone alkaloids Ruta graveolens CoA + 1,3-dihydroxy-N-methylacridone + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.159 ACS
-
 Ruta graveolens