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Literature summary extracted from

  • Svoronos, S.; Kumar, S.
    Decarboxylation of malonyl-CoA by lactating bovine mammary fatty acid synthase (1988), Comp. Biochem. Physiol. B, 90, 179-185.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.9 NEM no inhibition Bos taurus
4.1.1.9 p-hydroxymercuribenzoate insensitive Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.9 0.15
-
 malonyl-CoA
-
 Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.9 250000
-
 2 * 250000, SDS-PAGE Bos taurus
4.1.1.9 500000
-
 gel filtration Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.9 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.9 copurification of fatty acid synthetase and malonyl-CoA decarboxylase Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.9 Malonyl-CoA
-
 Bos taurus Acetyl-CoA + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.9 dimer 2 * 250000, SDS-PAGE Bos taurus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.9 6.5
-
-
 Bos taurus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.1.1.9 5.5 8 pH 5.5: about 80% of maximal activity, pH 8: about 40% of maximal activity Bos taurus