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Literature summary extracted from

  • Mawal, Y.R.; Qureshi, I.A.
    Purification to homogeneity of mitochondrial acyl CoA: glycine N-acyltransferase from human liver (1994), Biochem. Biophys. Res. Commun., 205, 1373-1379.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.13 K3PO4 100 mM, 68% inhibition Homo sapiens
2.3.1.13 K3PO4 100 mM, 43% inhibition Ovis aries
2.3.1.13 KCl 100 mM, 79% inhibition Homo sapiens
2.3.1.13 KCl 100 mM, 88% inhibition Ovis aries
2.3.1.13 NaCl 100 mM, 53% inhibition; 100 mM, 57% inhibition Homo sapiens
2.3.1.13 NaCl 100 mM, 57% inhibition Ovis aries

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.13 22.5
-
 benzoyl-CoA
-
 Ovis aries
2.3.1.13 35.6
-
 salicyl-CoA
-
 Ovis aries
2.3.1.13 57.9
-
 benzoyl-CoA
-
 Homo sapiens
2.3.1.13 73.3
-
 isovaleryl-CoA
-
 Ovis aries
2.3.1.13 83.7
-
 salicyl-CoA
-
 Homo sapiens
2.3.1.13 108.6
-
 octanoyl-CoA
-
 Ovis aries
2.3.1.13 124
-
 isovaleryl-CoA
-
 Homo sapiens
2.3.1.13 198
-
 octanoyl-CoA
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.13 30000
-
 1 * 30000, SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.13 Homo sapiens
-
-
-
2.3.1.13 Ovis aries
-
 ovine
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.13 ammonium sulfate, hydroxylapatite, Biogel P 100, Blue-dextran agarose, chromatofocusing Homo sapiens

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.13 13.9
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.13 acyl-CoA + glycine
-
 Homo sapiens CoA + N-acylglycine
-
 ?
2.3.1.13 acyl-CoA + glycine
-
 Ovis aries CoA + N-acylglycine
-
 ?
2.3.1.13 benzoyl-CoA + glycine
-
 Homo sapiens CoA + N-benzoylglycine
-
 ?
2.3.1.13 benzoyl-CoA + glycine
-
 Ovis aries CoA + N-benzoylglycine
-
 ?
2.3.1.13 isovaleryl-CoA + glycine
-
 Homo sapiens CoA + N-isovalerylglycine
-
 ?
2.3.1.13 isovaleryl-CoA + glycine
-
 Ovis aries CoA + N-isovalerylglycine
-
 ?
2.3.1.13 octanoyl-CoA + glycine
-
 Homo sapiens CoA + N-octanoylglycine
-
 ?
2.3.1.13 octanoyl-CoA + glycine
-
 Ovis aries CoA + N-octanoylglycine
-
 ?
2.3.1.13 salicyl-CoA + glycine
-
 Homo sapiens CoA + salicyluric acid
-
 ?
2.3.1.13 salicyl-CoA + glycine
-
 Ovis aries CoA + salicyluric acid
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.13 monomer
-
 Ovis aries
2.3.1.13 monomer 1 * 30000, SDS-PAGE Homo sapiens