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Literature summary extracted from

  • Negrel, J.; Javelle, F.
    L-Tyrosine beta-naphthylamide is a potent competitive inhibitor of tyramine N-(hydroxycinnamoyl)transferase in vitro (2001), Phytochemistry, 56, 523-527.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.110 L-phenylalanine beta-naphthylamide
-
 Nicotiana tabacum
2.3.1.110 L-phenylalanine beta-naphthylamide
-
 Solanum tuberosum
2.3.1.110 L-tyrosine 7-amido-4-methylcoumarin
-
 Nicotiana tabacum
2.3.1.110 L-tyrosine 7-amido-4-methylcoumarin
-
 Solanum tuberosum
2.3.1.110 L-tyrosine benzyl ester
-
 Nicotiana tabacum
2.3.1.110 L-tyrosine benzyl ester
-
 Solanum tuberosum
2.3.1.110 L-tyrosine beta-naphthylamide competitive with respect to tyramine, reversible in the presence of high concentrations of tyramine Nicotiana tabacum
2.3.1.110 L-tyrosine beta-naphthylamide competitive with respect to tyramine, reversible in the presence of high concentrations of tyramine Solanum tuberosum

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.110 Nicotiana tabacum
-
-
-
2.3.1.110 Solanum tuberosum
-
 potato
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.110
-
 Solanum tuberosum
2.3.1.110
-
 Nicotiana tabacum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.110 4-coumaroyl-CoA + tyramine
-
 Solanum tuberosum CoA + N-(4-coumaroyl)tyramine
-
 ?
2.3.1.110 4-coumaroyl-CoA + tyramine
-
 Nicotiana tabacum CoA + N-(4-coumaroyl)tyramine
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.1.110 0.0003
-
 L-tyrosine beta-naphthylamide
-
 Solanum tuberosum
2.3.1.110 0.00042
-
 L-tyrosine 7-amido-4-methylcoumarin
-
 Solanum tuberosum
2.3.1.110 0.00066
-
 L-tyrosine beta-naphthylamide
-
 Nicotiana tabacum
2.3.1.110 0.00072
-
 L-tyrosine 7-amido-4-methylcoumarin
-
 Nicotiana tabacum
2.3.1.110 0.003
-
 L-tyrosine benzyl ester
-
 Nicotiana tabacum
2.3.1.110 0.0034
-
 L-tyrosine benzyl ester
-
 Solanum tuberosum
2.3.1.110 0.091
-
 L-phenylalanine beta-naphthylamide
-
 Solanum tuberosum
2.3.1.110 0.112
-
 L-phenylalanine beta-naphthylamide
-
 Nicotiana tabacum