Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Baker, R.R.; Chang, H.Y.
    The potential for platelet-activating factor synthesis in brain: properties of cholinephosphotransferase and 1-alkyl-sn-glycero-3-phosphate acetyltransferase in microsomal fractions of immature rabbit cerebral cortex (1993), Biochim. Biophys. Acta, 1170, 157-164.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.105 1-alkyl-sn-glycero-3-phosphocholine small increase of activity Oryctolagus cuniculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.105 dithiothreitol
-
 Oryctolagus cuniculus
2.3.1.105 additional information not inhibited by 1-alkyl-sn-glycero-3-phosphocholine, 1-alkyl-sn-glycero-3-phosphocholine Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.105 0.11
-
 acetyl-CoA apparent Km for subcellular fraction R Oryctolagus cuniculus
2.3.1.105 0.137
-
 acetyl-CoA apparent Km for subcellular fraction P3 Oryctolagus cuniculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.105 cell body brain Oryctolagus cuniculus 44297
-
2.3.1.105 microsome
-
 Oryctolagus cuniculus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.1.105 Na+ activity appears maximal in the presence of NaF Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.105 acetyl-CoA + 1-alkyl-sn-glycero-3-phosphate Oryctolagus cuniculus
-
 CoA + 1-alkyl-2-acetyl-sn-glycero-3-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.105 Oryctolagus cuniculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.105 isolation of four subcellular fractions: S, R and P3 from cerebral cortices and P from nerve cell bodies Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.105 cerebral cortex
-
 Oryctolagus cuniculus
-
2.3.1.105 nerve brain Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.105 acetyl-CoA + 1-alkyl-sn-glycero-3-phosphate
-
 Oryctolagus cuniculus CoA + 1-alkyl-2-acetyl-sn-glycero-3-phosphate
-
 ?

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.3.1.105 8 9 subcellular fractions R and P3 Oryctolagus cuniculus
2.3.1.105 8.4 9 subcellular fractions P Oryctolagus cuniculus