EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.1 | arginine | 1 mM, 2-6fold activation of recombinant enzyme | Mus musculus |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.1 | expression in Escherichia coli | Mus musculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.1 | acetyl-CoA + L-glutamate | Mus musculus | first enzyme in urea cycle | CoA + N-acetyl-L-glutamate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.1 | Mus musculus | Q8R4H7 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.3.1.1 | recombinant enzyme, Ni2+-affinity column | Mus musculus |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.3.1.1 | 0.346 | - |
mature recombinant enzyme in the absence of arginine | Mus musculus |
2.3.1.1 | 0.803 | - |
mature recombinant enzyme in the presence of 1 mM arginine | Mus musculus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.1 | acetyl-CoA + L-glutamate | - |
Mus musculus | CoA + N-acetyl-L-glutamate | - |
? | |
2.3.1.1 | acetyl-CoA + L-glutamate | first enzyme in urea cycle | Mus musculus | CoA + N-acetyl-L-glutamate | - |
? |