Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Bachmann, C.; Krahenbuhl, S.; Colombo, J.P.
    Purification and properties of acetyl-CoA:L-glutamate N-acetyltransferase from human liver (1982), Biochem. J., 205, 123-127.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.1 N-acetyl-L-glutamate
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.1 4.4
-
 acetyl-CoA
-
 Homo sapiens
2.3.1.1 8.1
-
 glutamate
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.1 190000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.1 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.1 ammonium sulfate, hydroxyapatite, DEAE-cellulose, Sephacryl-300 Homo sapiens

Reaction

EC Number Reaction Comment Organism Reaction ID
2.3.1.1 acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate rapid-equilibrium random bi bi mechanism Homo sapiens
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.1 liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.1 0.00286
-
-
 Homo sapiens

Storage Stability

EC Number Storage Stability Organism
2.3.1.1 -20°C, stable for 2 months Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.1 acetyl-CoA + L-glutamate
-
 Homo sapiens CoA + N-acetyl-L-glutamate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.1 8.5
-
 liver enzyme, in the presence of arginine Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.1.1 0.49
-
 N-acetyl-L-glutamate
-
 Homo sapiens