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Literature summary extracted from

  • Leisinger, T.; Haas, D.
    N-Acetylglutamate synthase of Escherichia coli: regulation of synthesis and activity by arginine (1975), J. Biol. Chem., 250, 1690-1693.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.1 arginine 0.02 mM, 50% inhibition; L-arginine Escherichia coli
2.3.1.1 L-Indospicine 0.2 mM; 50% inhibition Escherichia coli
2.3.1.1 O-(L-Norvalyl-5)-isourea 0.02 mM, 50% inhibition Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.1 acetyl-CoA + L-glutamate Escherichia coli enzyme catalyzes the first step in the biosynthesis of arginine CoA + N-acetyl-L-glutamate
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 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.1 Escherichia coli
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 enzyme is repressed by arginine
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.1 acetyl-CoA + L-glutamate
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 Escherichia coli CoA + N-acetyl-L-glutamate
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 ?
2.3.1.1 acetyl-CoA + L-glutamate enzyme catalyzes the first step in the biosynthesis of arginine Escherichia coli CoA + N-acetyl-L-glutamate
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 ?