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Literature summary extracted from
- The isolation and preliminary characterization of apotransketolase from human erythrocytes (1982), Biochem. Biophys. Res. Commun., 106, 719-723.
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 2.2.1.1 | 0.0004 | - |
thiamine diphosphate | in the presence of Mg2+ | Homo sapiens |  |
| 2.2.1.1 | 0.18 | - |
D-xylulose 5-phosphate | (+ D-ribose 5-phosphate) | Homo sapiens | |
| 2.2.1.1 | 0.3 | - |
D-ribose 5-phosphate | cosubstrate D-xylulose 5-phosphate | Homo sapiens | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.2.1.1 | Mg2+ | no exogenous Mg2+-addition necessary | Homo sapiens | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.2.1.1 | D-xylulose 5-phosphate + D-ribose 5-phosphate | Homo sapiens | - |
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate | - |
r | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.2.1.1 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 2.2.1.1 | partial | Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 2.2.1.1 | erythrocyte | - |
Homo sapiens | - |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 2.2.1.1 | 4°C, at least 16 days | Homo sapiens |
| 2.2.1.1 | room temperature, after 13 days at 4°C, at least 4 h stable | Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.2.1.1 | D-xylulose 5-phosphate + D-ribose 5-phosphate | - |
Homo sapiens | sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate | - |
r | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 2.2.1.1 | 37 | - |
assay at | Homo sapiens |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 2.2.1.1 | 7.6 | 7.8 | - |
Homo sapiens |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.2.1.1 | thiamine diphosphate | not thiamine, thiamine mono-or triphosphate | Homo sapiens | |
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Release 2023.1 (January 2023)
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