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Literature summary extracted from

  • Koger, J.B.; Howell, R.G.; Kelly, M.; Jones, E.E.
    Purification and properties of porcine liver ornithine transcarbamylase (1994), Arch. Biochem. Biophys., 309, 293-299.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.3.3 Delta-N-Phosphonoacetyl-L-ornithine
-
 Sus scrofa
2.1.3.3 Phenylglyoxal complete inactivation after 1 h incubation Sus scrofa
2.1.3.3 phosphate
-
 Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.1.3.3 37000
-
 3 * 37000, SDS-PAGE Sus scrofa
2.1.3.3 107000
-
 gel filtration, sedimentation equilibrium Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
2.1.3.3 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.3.3 ammonium sulfate, Sephacryl S-200, delta-N-phosphonoacetyl-L-ornithine affinity chromatography Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.3.3 liver
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.1.3.3 26.4
-
-
 Sus scrofa

Storage Stability

EC Number Storage Stability Organism
2.1.3.3 -20°C, several weeks, no loss of activity Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.3.3 carbamoyl phosphate + L-ornithine
-
 Sus scrofa phosphate + L-citrulline
-
 ?

Subunits

EC Number Subunits Comment Organism
2.1.3.3 trimer 3 * 37000, SDS-PAGE Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.1.3.3 8
-
 sharp decrease in activity between pH 8.4 and 8.8 Sus scrofa

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.1.3.3 0.00013
-
 Delta-N-Phosphonoacetyl-L-ornithine
-
 Sus scrofa