Literature summary extracted from

Mori, M.; Aoyagi, K.; Tatibana, M.; Ishikawa, T.; Ishii, H.
N delta-(phosphonacetyl)-L-ornithine, a potent transition state analogue inhibitor of ornithine carbamoyltransferase (1977), Biochem. Biophys. Res. Commun., 76, 900-904.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.1.3.3	Delta-N-Phosphonoacetyl-L-ornithine	competitive vs. carbamoylphosphate; transition state analogue	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.3.3	Bos taurus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.1.3.3	liver	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.3.3	carbamoyl phosphate + L-ornithine	-	Bos taurus	phosphate + L-citrulline	-	?

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
2.1.3.3	0.0000047	-	Delta-N-Phosphonoacetyl-L-ornithine	at pH 8.5	Bos taurus
2.1.3.3	0.000007	-	Delta-N-Phosphonoacetyl-L-ornithine	at pH 7.2	Bos taurus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)