BRENDA - Enzyme Database

Are carboxylations involving biotin concerted or nonconcerted?

Stubbe, J.; Fish, S.; Abeles, R.H.; J. Biol. Chem. 255, 236-242 (1980) View publication on PubMed

Data extracted from this reference:

Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
2.1.3.1
Co2+
requirement
Propionibacterium sp.
Organism
EC Number
Organism
UniProt
Commentary
Textmining
2.1.3.1
Propionibacterium sp.
-
-
-
Reaction
EC Number
Reaction
Commentary
Organism
Reaction ID
2.1.3.1
(S)-methylmalonyl-CoA + pyruvate = propanoyl-CoA + oxaloacetate
mechanism
Propionibacterium sp.
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
2.1.3.1
3-fluoropropionyl-CoA + oxaloacetate
no F-release if pyruvate or malate are substituted for oxaloacetate
485821
Propionibacterium sp.
acrylyl-CoA + pyruvate + F- + CO2
-
485821
Propionibacterium sp.
?
Temperature Optimum [°C]
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
2.1.3.1
28
-
assay at
Propionibacterium sp.
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
2.1.3.1
biotin
requirement
Propionibacterium sp.
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
2.1.3.1
biotin
requirement
Propionibacterium sp.
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
2.1.3.1
Co2+
requirement
Propionibacterium sp.
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
2.1.3.1
3-fluoropropionyl-CoA + oxaloacetate
no F-release if pyruvate or malate are substituted for oxaloacetate
485821
Propionibacterium sp.
acrylyl-CoA + pyruvate + F- + CO2
-
485821
Propionibacterium sp.
?
Temperature Optimum [°C] (protein specific)
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
2.1.3.1
28
-
assay at
Propionibacterium sp.