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Literature summary extracted from

  • McMorran, B.J.; Kumara, H.M.C.S.; Sullivan, K.; Lamont, I.L.
    Involvement of a transformylase enzyme in siderophore synthesis in Pseudomonas aeruginosa (2001), Microbiology, 147, 1517-1524.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.2.2
-
 Pseudomonas aeruginosa
2.1.2.2 pvdF gene characterization Pseudomonas aeruginosa

Protein Variants

EC Number Protein Variants Comment Organism
2.1.2.2 additional information enzyme disruption mutant, no synthesis of pyoverdine, mutant strain is unable to grow on King´s B agar containing iron-chelating agent EDTA Pseudomonas aeruginosa

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.1.2.2 Fe2+ expression regulated by amount of iron in the growth medium Pseudomonas aeruginosa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.1.2.2 30985
-
 x * 30985, calculated Pseudomonas aeruginosa
2.1.2.2 31000
-
 DNA sequencing Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide Drosophila melanogaster
-
 tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide Bacillus subtilis
-
 tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide Saccharomyces cerevisiae
-
 tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide Arabidopsis thaliana
-
 tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide Pseudomonas aeruginosa involved in pyoverdine synthesis tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.2.2 Arabidopsis thaliana
-
-
-
2.1.2.2 Bacillus subtilis
-
-
-
2.1.2.2 Drosophila melanogaster
-
 fruit fly
-
2.1.2.2 Escherichia coli
-
-
-
2.1.2.2 Pseudomonas aeruginosa
-
-
-
2.1.2.2 Saccharomyces cerevisiae
-
 yeast
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
 Drosophila melanogaster tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
 Bacillus subtilis tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
 Escherichia coli tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
 Saccharomyces cerevisiae tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
 Arabidopsis thaliana tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
 Pseudomonas aeruginosa tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide involved in pyoverdine synthesis Pseudomonas aeruginosa tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + N5-hydroxyornithine
-
 Pseudomonas aeruginosa tetrahydrofolate + N5-formyl-N5-hydroxyornithine
-
 ?

Subunits

EC Number Subunits Comment Organism
2.1.2.2 ? x * 30985, calculated Pseudomonas aeruginosa

Synonyms

EC Number Synonyms Comment Organism
2.1.2.2 GART synthetase
-
 Drosophila melanogaster
2.1.2.2 GART synthetase
-
 Bacillus subtilis
2.1.2.2 GART synthetase
-
 Escherichia coli
2.1.2.2 GART synthetase
-
 Saccharomyces cerevisiae
2.1.2.2 GART synthetase
-
 Arabidopsis thaliana