EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.1.2.2 | 110000 | 120000 | gel filtration, sucrose density gradient ultracentrifugation, sedimentation velocity | Gallus gallus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.2.2 | 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide | Gallus gallus | essential enzyme in DNA synthesis, third enzyme in de novo purine biosynthesis pathway | tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide | - |
? | |
2.1.2.2 | 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide | Escherichia coli | essential enzyme in DNA synthesis, third enzyme in de novo purine biosynthesis pathway | tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide | - |
? | |
3.5.4.9 | 5,10-methenyltetrahydrofolate + H2O | Gallus gallus | - |
10-formyltetrahydrofolate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.1.2.2 | Escherichia coli | - |
- |
- |
2.1.2.2 | Gallus gallus | - |
chicken | - |
3.5.4.9 | Gallus gallus | - |
chicken, trifunctional enzyme | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.1.2.2 | copurification of trifunctional 5,10-methenyl-, 5,10-methylene, and 10-formylH4folate synthetase, aminoimidazole carboxamide ribotide transformylase and serine transhydroxymethylase | Gallus gallus |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.5.4.9 | 30.6 | - |
- |
Gallus gallus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.2.2 | 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide | - |
Gallus gallus | tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide | - |
? | |
2.1.2.2 | 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide | - |
Escherichia coli | tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide | - |
? | |
2.1.2.2 | 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide | essential enzyme in DNA synthesis, third enzyme in de novo purine biosynthesis pathway | Gallus gallus | tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide | - |
? | |
2.1.2.2 | 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide | essential enzyme in DNA synthesis, third enzyme in de novo purine biosynthesis pathway | Escherichia coli | tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide | - |
? | |
2.1.2.2 | additional information | trifunctional enzyme, GAR synthetase, aminoimidazole ribonucleotide synthetase and GAR transformylase | Gallus gallus | ? | - |
? | |
3.5.4.9 | 5,10-methenyltetrahydrofolate + H2O | - |
Gallus gallus | 10-formyltetrahydrofolate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.1.2.2 | dimer | - |
Escherichia coli |
2.1.2.2 | dimer | 2 * 55000-57000, SDS-PAGE | Gallus gallus |