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Literature summary extracted from

  • Dev, I.K.; Harvey, R.J.
    N10-Formyltetrahydrofolate is the formyl donor for glycinamide ribonucleotide transformylase in Escherichia coli (1978), J. Biol. Chem., 253, 4242-4244.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.1.2.2 0.21
-
 N-formylglycinamide ribotide
-
 Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide Salmonella enterica subsp. enterica serovar Typhimurium
-
 tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide Gallus gallus
-
 tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.2.2 Escherichia coli
-
-
-
2.1.2.2 Escherichia coli B / ATCC 11303
-
-
-
2.1.2.2 Gallus gallus
-
 chicken
-
2.1.2.2 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.2.2
-
 Escherichia coli
2.1.2.2 partially Gallus gallus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.2.2 liver
-
 Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
 Salmonella enterica subsp. enterica serovar Typhimurium tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
 Gallus gallus tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
 Escherichia coli tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
 Escherichia coli B / ATCC 11303 tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + beta-5-phospho-D-ribosylglycinamide
-
 Escherichia coli tetrahydrofolate + beta-5'-phosphoribosyl-N-formylglycinamide
-
 ?
2.1.2.2 10-formyltetrahydrofolate + beta-5-phospho-D-ribosylglycinamide
-
 Escherichia coli B / ATCC 11303 tetrahydrofolate + beta-5'-phosphoribosyl-N-formylglycinamide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.2.2 N10-formyltetrahydrolate:2-amino-N-ribosylacetamide-5'-phosphate transformylase
-
 Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
2.1.2.2 N10-formyltetrahydrofolate
-
 Gallus gallus
2.1.2.2 N10-formyltetrahydrofolate only formyldonor Escherichia coli
2.1.2.2 N5,N10-methenyltetrahydrofolate
-
 Salmonella enterica subsp. enterica serovar Typhimurium