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Literature summary extracted from

  • Sharma, S.K.; Garrett, J.M.; Brown, S.A.
    Separation of the S-adenosylmethionine: 5-and 8-hydroxyfuranocoumarin O-methyltransferases of Ruta graveolens L. by general ligand affinity chromatography (1979), Z. Naturforsch. C, 34, 387-391.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.69 S-adenosyl-L-methionine + bergaptol Ruta graveolens furanocoumarinbiosynthesis S-adenosyl-L-homocysteine + bergapten
-
?
2.1.1.70 S-adenosyl-L-methionine + xanthotoxol Ruta graveolens furanocoumarin biosynthesis S-adenosyl-L-homocysteine + xanthotoxin
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.69 Ruta graveolens
-
-
-
2.1.1.70 Ruta graveolens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.69 partial Ruta graveolens
2.1.1.70 partial Ruta graveolens

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.1.1.69 0.000375
-
-
Ruta graveolens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.69 additional information no activity against xanthoxol Ruta graveolens ?
-
?
2.1.1.69 S-adenosyl-L-methionine + 5-hydroxyxanthotoxin
-
Ruta graveolens S-adenosyl-L-homocysteine + isopimpinellin
-
?
2.1.1.69 S-adenosyl-L-methionine + bergaptol
-
Ruta graveolens S-adenosyl-L-homocysteine + bergapten
-
?
2.1.1.69 S-adenosyl-L-methionine + bergaptol furanocoumarinbiosynthesis Ruta graveolens S-adenosyl-L-homocysteine + bergapten
-
?
2.1.1.70 S-adenosyl-L-methionine + xanthotoxol
-
Ruta graveolens S-adenosyl-L-homocysteine + xanthotoxin
-
?
2.1.1.70 S-adenosyl-L-methionine + xanthotoxol furanocoumarin biosynthesis Ruta graveolens S-adenosyl-L-homocysteine + xanthotoxin
-
?

Cofactor

EC Number Cofactor Comment Organism Structure
2.1.1.69 S-adenosyl-L-methionine
-
Ruta graveolens
2.1.1.70 S-adenosyl-L-methionine
-
Ruta graveolens